Transcriptional regulation and transformation by Myc proteins.

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Abstract

Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.

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Journal

Journal ID (iso-abbrev): Nat Rev Mol Cell Biol

Title: Nature reviews. Molecular cell biology

Publisher: Springer Science and Business Media LLC

ISSN: 1471-0072

ISSN (Print): 1471-0072

Publication date (Electronic): Aug 2005

Volume: 6

Issue: 8

Affiliations

[1 ] Institute for Molecular Biology and Tumour Research, University of Marburg, Emil-Mannkopff-Strasse 2, 35033 Marburg, Germany.

Article

Publisher Item ID: nrm1703

DOI: 10.1038/nrm1703

PubMed ID: 16064138

SO-VID: 9baa9363-3aa8-4b01-904f-790f467c23bc

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