To assess the impact of the different types of contact lenses (CLs) on quality of life (QoL) in patients with keratoconus based on self-reported results from The Contact Lens Impact on Quality of Life (CLIQ) Questionnaire. Consecutive keratoconus patients who wore CLs (rigid gas permeable [RGP], hybrid or soft toric) at least in one eye were asked to complete the CLIQ questionnaire on the Cornea Service, Wills Eye Institute. A total of 71 patients with a mean age of 42.6 +/- 13.1 year were included in the study. One eye of each patient was included in the study. Of these, 40 eyes used rigid gas-permeable lenses, 20 eyes used hybrid lenses and 11 eyes used soft toric lenses. The mean CLIQperson measure was 45.5 +/- 8.2 in RGP group, 45.4 +/- 7.5 in hybrid group and 48.4 +/- 10.5 in soft toric group. There was no significant difference among the three groups in self-reported results from the CLIQ questionnaire (P = 0.8). Subjects with keratoconus who wear RGP, hybrid or soft toric CLs, reported similar contact lens impact on their QoL.