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      Acupuncture — from empiricism to science: Functional background to acupuncture effects in pain and disease Pain and disease

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      Medical Hypotheses
      Elsevier BV

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          Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry.

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            Endogenous opioids: biology and function.

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              beta-Endorphin and adrenocorticotropin are selected concomitantly by the pituitary gland.

              The opiate-like peptide beta-endorphin and adrenocorticotropin are concomitantly secreted in increased amounts by the adenohypophysis in response to acute stress or long-term adrenalectomy as well as in vitro in response to purified corticotropin releasing factor and other secretagogues. Conversely, administration of the synthetic glucocorticoid dexamethasone inhibits the secretion of both adrenocorticotropin and beta-endorphin. Thus, both hormones possess common and identical regulatory mechanisms and there may be a functional role for circulating beta-endorphin.
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                Author and article information

                Journal
                Medical Hypotheses
                Medical Hypotheses
                Elsevier BV
                03069877
                September 1995
                September 1995
                : 45
                : 3
                : 271-281
                Article
                10.1016/0306-9877(95)90117-5
                98ac5d51-a39d-4cd9-8b67-19b37614d78a
                © 1995

                http://www.elsevier.com/tdm/userlicense/1.0/

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