Contributors
Jennifer K. Pleiman: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: ResourcesRole:
ValidationRole: Writing – original draftRole: Writing – review & editing
Amy A. Irving: Role: InvestigationRole: ResourcesRole: Writing – review & editing
Zhishi Wang: Role: Software
Erik Toraason: Role: InvestigationRole: Writing – review & editing
Linda Clipson: Role: Data curationRole: Formal analysisRole: VisualizationRole: Writing – original
draft
William F. Dove:
ORCID: http://orcid.org/0000-0002-8666-6895
Role: ConceptualizationRole: Funding acquisitionRole: MethodologyRole: Project administrationRole:
ResourcesRole: SupervisionRole: Writing – original draftRole: Writing – review & editing
Dustin A. Deming: Role: Funding acquisitionRole: ValidationRole: Writing – review & editing
Michael A. Newton: Role: Formal analysisRole: Funding acquisitionRole: MethodologyRole: SoftwareRole:
SupervisionRole: ValidationRole: VisualizationRole: Writing – original draftRole:
Writing – review & editing
David R. Beier: Role: Editor
Journal
Journal ID (nlm-ta): PLoS Genet
Journal ID (iso-abbrev): PLoS Genet
Journal ID (publisher-id): plos
Journal ID (pmc): plosgen
Title:
PLoS Genetics
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7390
ISSN
(Electronic):
1553-7404
Publication date
(Electronic):
6
September
2018
Publication date Collection:
September
2018
Volume: 14
Issue: 9
Electronic Location Identifier: e1007611
Affiliations
[1
]
McArdle Laboratory for Cancer Research, Department of Oncology, University of Wisconsin–Madison,
Madison, Wisconsin, United States of America
[2
]
Laboratory of Genetics, University of Wisconsin–Madison, Madison, Wisconsin, United
States of America
[3
]
Molecular and Environmental Toxicology Center, University of Wisconsin–Madison, Madison,
Wisconsin, United States of America
[4
]
Department of Statistics, University of Wisconsin–Madison, Madison, Wisconsin, United
States of America
[5
]
Carbone Cancer Center, University of Wisconsin–Madison, Madison, Wisconsin, United
States of America
[6
]
Division of Hematology and Medical Oncology, Department of Medicine, University of
Wisconsin–Madison, Madison, Wisconsin, United States of America
[7
]
Department of Biostatistics and Medical Informatics, University of Wisconsin–Madison,
Madison, Wisconsin, United States of America
Seattle Children’s Research Institute, UNITED STATES
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PGENETICS-D-17-02463
DOI: 10.1371/journal.pgen.1007611
PMC ID: 6143270
PubMed ID: 30188895
SO-VID: 96c518b5-1ebe-46a6-9285-272f71126359
Copyright © © 2018 Pleiman et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 19
December
2017
Date
accepted
: 6
August
2018
Page count
Figures: 11,
Tables: 2,
Pages: 26
Funding
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: R37 CA063677
Award Recipient
:
ORCID: http://orcid.org/0000-0002-8666-6895
William F. Dove
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: U54 A1-117924
Award Recipient
:
Michael A. Newton
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: T32 GM007133
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: T32 ES007015
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: P30 CA014520
Funded by: Morgridge Fellowship in Biotechnology
Award Recipient
:
Amy A. Irving
Support for this study was provided by National Institutes of Health grants (WFD)
R37 CA063677; (MAN) U54 A1-117924; (JKP) T32 GM007133 (Genetics); (AAI) T32 ES007015
(Environmental Toxicology) and Morgridge Fellowship in Biotechnology; and (WFD, MAN,
and DAD) P30 CA014520 (Carbone Cancer Center). The funders had no role in study design,
data collection and analysis, decision to publish, or preparation of the manuscript.
Categories
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Digestive System
Subject:
Gastrointestinal Tract
Subject:
Colon
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Digestive System
Subject:
Gastrointestinal Tract
Subject:
Colon
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Adenomas
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Colorectal Cancer
Subject:
Research and Analysis Methods
Subject:
Experimental Organism Systems
Subject:
Model Organisms
Subject:
Mouse Models
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Mouse Models
Subject:
Research and Analysis Methods
Subject:
Experimental Organism Systems
Subject:
Animal Models
Subject:
Mouse Models
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
Antigen-Presenting Cells
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
Antigen-Presenting Cells
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
Antigen-Presenting Cells
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancer Treatment
Subject:
Medicine and Health Sciences
Subject:
Gastroenterology and Hepatology
Subject:
Inflammatory Bowel Disease
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