Salvianolic acid B accelerated ABCA1-dependent cholesterol efflux by targeting PPAR-γ and LXRα

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Abstract

Cholesterol efflux has been thought to be the main and basic mechanism by which free cholesterol is transferred from extra hepatic cells to the liver or intestine for excretion. Salvianolic acid B (Sal B) has been widely used for the prevention and treatment of atherosclerotic diseases. Here, we sought to investigate the effects of Sal B on the cholesterol efflux in THP-1 macrophages.

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Journal

Title: Biochemical and Biophysical Research Communications

Abbreviated Title: Biochemical and Biophysical Research Communications

Publisher: Elsevier BV

ISSN (Print): 0006291X

Publication date Created: July 2015

Publication date (Print): July 2015

Volume: 462

Issue: 3

Pages: 233-238

Article

DOI: 10.1016/j.bbrc.2015.04.122

PubMed ID: 25956064

SO-VID: 9661e9df-f0ac-40d6-8e8b-1faf47dd643a

License:

https://www.elsevier.com/tdm/userlicense/1.0/

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Salvianolic acid B accelerated ABCA1-dependent cholesterol efflux by targeting PPAR-γ and LXRα

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