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      How to diagnose acute appendicitis: ultrasound first

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          Abstract

          Acute appendicitis (AA) is a common abdominal emergency with a lifetime prevalence of about 7 %. As the clinical diagnosis of AA remains a challenge to emergency physicians and surgeons, imaging modalities have gained major importance in the diagnostic work-up of patients with suspected AA in order to keep both the negative appendectomy rate and the perforation rate low. Introduced in 1986, graded-compression ultrasound (US) has well-established direct and indirect signs for diagnosing AA. In our opinion, US should be the first-line imaging modality, as graded-compression US has excellent specificity both in the paediatric and adult patient populations. As US sensitivity is limited, and non-diagnostic US examinations with non-visualization of the appendix are more a rule than an exception, diagnostic strategies and algorithms after non-diagnostic US should focus on clinical reassessment and complementary imaging with MRI/CT if indicated. Accordingly, both ionizing radiation to our patients and cost of pre-therapeutic diagnosis of AA will be low, with low negative appendectomy and perforation rates.

          Main Messages

          Ultrasound (US) should be the first imaging modality for diagnosing acute appendicitis (AA).

          Primary US for AA diagnosis will decrease ionizing radiation and cost.

          Sensitivity of US to diagnose AA is lower than of CT/MRI.

          Non-visualization of the appendix should lead to clinical reassessment.

          Complementary MRI or CT may be performed if diagnosis remains unclear.

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          Most cited references48

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          The epidemiology of appendicitis and appendectomy in the United States.

          To describe the epidemiology of appendicitis and appendectomy in the United States, the authors analyzed National Hospital Discharge Survey data for the years 1979-1984. Approximately 250,000 cases of appendicitis occurred annually in the United States during this period, accounting for an estimated 1 million hospital days per year. The highest incidence of primary positive appendectomy (appendicitis) was found in persons aged 10-19 years (23.3 per 10,000 population per year); males had higher rates of appendicitis than females for all age groups (overall rate ratio, 1.4:1). Racial, geographic, and seasonal differences were also noted. Appendicitis rates were 1.5 times higher for whites than for nonwhites, highest (15.4 per 10,000 population per year) in the west north central region, and 11.3% higher in the summer than in the winter months. The highest rate of incidental appendectomy was found in women aged 35-44 years (43.8 per 10,000 population per year), 12.1 times higher than the rate for men of the same age. Between 1970 and 1984, the incidence of appendicitis decreased by 14.6%; reasons for this decline are unknown. A life table model suggests that the lifetime risk of appendicitis is 8.6% for males and 6.7% for females; the lifetime risk of appendectomy is 12.0% for males and 23.1% for females. Overall, an estimated 36 incidental procedures are performed to prevent one case of appendicitis; for the elderly, the preventive value of an incidental procedure is considerably lower.
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            Acute appendicitis.

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              Appendicitis at the millennium.

              Acute appendicitis is a common clinical problem. Accurate and prompt diagnosis is essential to minimize morbidity. While the clinical diagnosis may be straightforward in patients who present with classic signs and symptoms, atypical presentations may result in diagnostic confusion and delay in treatment. Helical computed tomography (CT) and graded compression color Doppler ultrasonography (US) are highly accurate means of establishing the diagnosis. These imaging modalities have now assumed critical roles in the treatment of patients suspected to have appendicitis. The purpose of this article is threefold: to provide an update on new information regarding the pathophysiology, clinical diagnosis, and laparoscopic treatment of acute appendicitis; to describe the state-of-the art use of CT and US in diagnosing this disease entity; and to address the role of medical imaging in this patient population.
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                Author and article information

                Contributors
                gerhard.mostbeck@chello.at
                Journal
                Insights Imaging
                Insights Imaging
                Insights into Imaging
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                1869-4101
                16 February 2016
                16 February 2016
                April 2016
                : 7
                : 2
                : 255-263
                Affiliations
                [ ]Department of Radiology, Wilhelminenspital, Montleartstr., 37 1160 Vienna, Austria
                [ ]St George’s Hospital, Blackshaw Road, SW17 0QT London, UK
                [ ]Department of Radiology, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
                [ ]Children Hospital, University Hospital-Nancy Brabois, Rue du Morvan, 54511 Vandoeuvre Les Nancy Cedex, France
                [ ]Munich University Hospital, Marchioninistraße. 15, 81377 München, Germany
                [ ]Radiology Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
                [ ]Radiology Department, City Hospitals Sunderland FT, Kayll Road, Sunderland, SR4 7TP UK
                [ ]Department of Radiology, Great Ormond Street, WC1N, 3JH London, UK
                Article
                469
                10.1007/s13244-016-0469-6
                4805616
                26883138
                9527333e-6e57-4bea-b35d-4e56301db336
                © The Author(s) 2016

                Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

                History
                : 7 October 2015
                : 18 January 2016
                : 25 January 2016
                Categories
                Opinion
                Custom metadata
                © The Author(s) 2016

                Radiology & Imaging
                appendicitis,ultrasound,computed tomography,magnetic resonance imaging,diagnostic algorithm

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