Contributors
Ryan J. Longchamps: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Writing – original
draftRole: Writing – review & editing
Christina A. Castellani:
ORCID: http://orcid.org/0000-0003-2737-0549
Role: Data curationRole: Formal analysisRole: Writing – review & editing
Stephanie Y. Yang: Role: Data curationRole: Formal analysisRole: Writing – review & editing
Charles E. Newcomb:
ORCID: http://orcid.org/0000-0002-2646-7288
Role: Data curationRole: Formal analysisRole: Writing – review & editing
Jason A. Sumpter: Role: Data curationRole: Formal analysisRole: Writing – review & editing
John Lane: Role: Formal analysisRole: SoftwareRole: Writing – review & editing
Megan L. Grove: Role: Data curationRole: Project administrationRole: ResourcesRole: Writing – review
& editing
Eliseo Guallar: Role: ConceptualizationRole: Funding acquisitionRole: SupervisionRole: Writing – review
& editing
Nathan Pankratz: Role: ConceptualizationRole: SupervisionRole: Writing – review & editing
Kent D. Taylor:
ORCID: http://orcid.org/0000-0002-2756-4370
Role: Data curationRole: Funding acquisitionRole: Writing – review & editing
Jerome I. Rotter:
ORCID: http://orcid.org/0000-0001-7191-1723
Role: Data curationRole: Funding acquisitionRole: SupervisionRole: Writing – review
& editing
Eric Boerwinkle: Role: Data curationRole: Funding acquisitionRole: SupervisionRole: Writing – review
& editing
Dan E. Arking:
ORCID: http://orcid.org/0000-0001-8980-8695
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
SupervisionRole: Writing – original draftRole: Writing – review & editing
David C. Samuels: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
31
January
2020
Publication date Collection: 2020
Volume: 15
Issue: 1
Electronic Location Identifier: e0228166
Affiliations
[1
]
Department of Genetic Medicine, McKusick-Nathans Institute, Johns Hopkins University
School of Medicine, Baltimore, MD, United States of America
[2
]
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School,
Minneapolis, MN, United States of America
[3
]
Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental
Sciences, School of Public Health, The University of Texas Health Science Center at
Houston, Houston, TX, United States of America
[4
]
Department of Epidemiology and the Welch Center for Prevention, Epidemiology and Clinical
Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States
of America
[5
]
LABioMed and Department of Pediatrics, at Harbor-UCLA Medical Center, Institute for
Translational Genomics and Population Sciences, Torrance, CA, United States of America
[6
]
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, United States
of America
Vanderbilt University Medical Center, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-19-28415
DOI: 10.1371/journal.pone.0228166
PMC ID: 6994099
PubMed ID: 32004343
SO-VID: 94ffd930-5a24-4d6c-8eec-1f45fe218cc1
Copyright © © 2020 Longchamps et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 10
October
2019
Date
accepted
: 8
January
2020
Page count
Figures: 3,
Tables: 2,
Pages: 14
Funding
This research was supported by grant R01HL131573 from the US National Institutes of
Health (Longchamps, Castellani, Guallar, and Arking) and by grant P30AG021334 from
the Johns Hopkins University Claude D. Pepper Older Americans Independence Center
National Institute on Aging (Dr Arking). The Atherosclerosis Risk in Communities study
has been funded in whole or in part with Federal funds from the National Heart, Lung,
and Blood Institute, National Institutes of Health, Department of Health and Human
Services, under Contract nos. (HHSN268201700001I, HHSN268201700002I, HHSN268201700003I,
HHSN268201700005I, HHSN268201700004I). The Multi-Ethnic Study of Atherosclerosis is
supported by contracts HHSN268201500003I, N01-HC 95159, N01-HC-95160, N01-HC-95161,
N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167,
N01-HC-95168 and N01-HC-95169 from the National Heart, Lung, and Blood Institute,
and by grants UL1-TR-000040, UL1-TR-001079, and UL1-TR-001420 from the National Center
for Advancing Translational Sciences (NCATS). Dr. Rotter and Dr. Taylor’s efforts
were supported in part by the National Center for Advancing Translational Sciences,
CTSI grant UL1TR001881, and the National Institute of Diabetes and Digestive and Kidney
Disease Diabetes Research Center (DRC) grant DK063491 to the Southern California Diabetes
Endocrinology Research Center. Funding for SHARe genotyping was provided by National
Heart, Lung, and Blood Institute contract N02-HL-64278. The funding organizations
had no role in the design and conduct of the study; collection, management, analysis,
and interpretation of the data; preparation, review, or approval of the manuscript;
and decision to submit the manuscript for publication.
Categories
Subject:
Research Article
Subject:
Research and analysis methods
Subject:
Extraction techniques
Subject:
DNA extraction
Subject:
Medicine and Health Sciences
Subject:
Cardiovascular Medicine
Subject:
Cardiovascular Diseases
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Biology and Life Sciences
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Biochemistry
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Bioenergetics
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Energy-Producing Organelles
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Mitochondria
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Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Structures and Organelles
Subject:
Energy-Producing Organelles
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Mitochondria
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Research and Analysis Methods
Subject:
Bioassays and Physiological Analysis
Subject:
Microarrays
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Genotyping
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Genotyping
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
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Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Biology and Life Sciences
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Cell Biology
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Cellular Types
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Animal Cells
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Immune Cells
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White Blood Cells
Subject:
Biology and Life Sciences
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Immunology
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Immune Cells
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White Blood Cells
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Medicine and Health Sciences
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Immunology
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Immune Cells
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White Blood Cells
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Biology and Life Sciences
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Genetics
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Molecular Genetics
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Genetics
Subject:
Research and Analysis Methods
Subject:
Database and Informatics Methods
Subject:
Bioinformatics
Subject:
Sequence Analysis
Subject:
Sequence Alignment
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