Clinical Outcomes of Renin-Angiotensin-Aldosterone Blockade in Patients With Advanced Chronic Kidney Disease: A Systematic Review and Meta-analysis.

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Abstract

The cardiovascular and renal benefits of renin-angiotensin aldosterone system (RAAS) blockade are not well established in patients with advanced chronic kidney disease (CKD). We conducted a systematic review and meta-analysis to identify potential risks and benefits from RAAS blockade in patients with CKD stage 4-5.

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Journal

Journal ID (iso-abbrev): Can J Cardiol

Title: The Canadian journal of cardiology

Publisher: Elsevier BV

ISSN (Electronic): 1916-7075

ISSN (Print): 0828-282X

Publication date (Electronic): Sep 2024

Volume: 40

Issue: 9

Affiliations

[1 ] Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada; Faculty of Medicine and Health Sciences, McGill University, Montréal, Québec, Canada. Electronic address: nicolas.vendeville@mail.mcgill.ca.

[2 ] Faculty of Medicine and Health Sciences, McGill University, Montréal, Québec, Canada.

[3 ] Division of Nephrology, Department of Medicine, McGill University Health Centre, Montréal, Québec, Canada; Research Institute, McGill University Health Centre, Montréal, Québec, Canada.

Article

Publisher Item ID: S0828-282X(24)00192-2

DOI: 10.1016/j.cjca.2024.02.027

PubMed ID: 38458564

SO-VID: 9467c271-44ff-43bc-844e-6ebf5175b255

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