Levetiracetam: safety and efficacy in neonatal seizures.

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Abstract

Neonatal seizures are common, especially in prematurity. Phenobarbital (PB) currently represents the antiepileptic drug (AED) of choice, despite being related to increased neuronal apoptosis in animal models and cognitive impairment in human subjects. Levetiracetam (LEV) may have a more favorable profile since it does not cause neuronal apoptosis in infant rodents.

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Journal

Journal ID (iso-abbrev): Eur J Paediatr Neurol

Title: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Publisher: Elsevier BV

ISSN (Electronic): 1532-2130

ISSN (Print): 1090-3798

Publication date (Electronic): Jan 2011

Volume: 15

Issue: 1

Affiliations

[1 ] Department of Pediatric Neurology, University Children's Hospital Dresden, Fetscherstrasse 74, 01307 Dresden, Germany. georgia.ramantani@uniklinik-freiburg.de

Article

Publisher Item ID: S1090-3798(10)00190-X

DOI: 10.1016/j.ejpn.2010.10.003

PubMed ID: 21094062

SO-VID: 94447ea3-43e5-4ca3-8fbc-b224d965d677

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