Surface-plasmon-resonance-based optical-fiber temperature sensor with high sensitivity and high figure of merit

Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels. This review article discusses a wide range of applications in optical-based sensors using either surface plasmon resonance (SPR) or surface plasmon resonance imaging (SPRI). Here we summarize the principles, provide examples, and illustrate the utility of SPR and SPRI through example applications from the biomedical, proteomics, genomics and bioengineering fields. In addition, SPR signal amplification strategies and surface functionalization are covered in the review.

We present a novel scheme for simultaneous measurement of temperature and refractive index by use of a single sampled fiber Bragg grating (SFBG). The intrinsic nature of a SFBG that possesses both fiber Bragg grating and long-period grating spectral responses permits the temperature effect to the measured solely from the former, whereas the refractive-index information is extracted from the latter. Using such a dual-parameter sensor, we successfully demonstrated measurement of the dependence on temperature of the refractive index of an aqueous solution of sucrose.