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      Deep anterior lamellar keratoplasty for the management of iatrogenic keratectasia occurring after hexagonal keratotomy

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          Abstract

          Iatrogenic keratectasia has been reported subsequent to refractive surgery or trauma. Hexagonal keratotomy (HK) is a surgical incisional technique to correct hyperopia. A number of complications have been reported following this procedure, including irregular astigmatism, wound healing abnormalities and corneal ectasia. When visual acuity is poor because of ectasia or irregular astigmatism and contact lens fitting is not possible, penetrating or lamellar keratoplasty can be performed. Since incisions in refractive keratotomy are set at 90–95% depth of cornea, intraoperative microperforations are known to occur and lamellar keratoplasty may become difficult. We describe deep anterior lamellar keratoplasty (DALK) used to successfully manage keratectasia after HK. Pre DALK vision was 20/400 and post DALK vision was 20/30 two months after surgery. This report aims to show improved visual outcome in corneal ectasia secondary to HK. DALK can be a procedure of choice with proper case selection.

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          Most cited references9

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          Current treatment options for corneal ectasia.

          The approach to the management of various forms of corneal ectasia is changing, with the advent of new surgical and nonsurgical options. The purpose of this review is to summarize and evaluate relevant studies on new treatments for keratoconus, postrefractive surgery keratectasia, and peripheral ectatic corneal disorders. Various alternatives to corneal transplantation for the management of keratoconus aim to enhance corneal rigidity by means of nonsurgical collagen cross-linking, or with the use of intrastromal corneal ring segments, and studies suggest that these treatments may reduce astigmatism or ectatic progression to varying degrees. Recent developments in anterior lamellar keratoplasty enable targeted replacement or augmentation of corneal stroma without replacement of endothelium, and include procedures such as deep anterior lamellar keratoplasty, microkeratome or laser-assisted anterior lamellar surgery, and peripheral tectonic lamellar keratoplasty procedures demonstrate successful reinforcement of peripheral stroma to reduce astigmatism. These new forms of surgery are viable alternatives to conventional penetrating keratoplasty and bring added safety profiles for long-term visual rehabilitation and restoration of tectonic integrity in central and peripheral forms of corneal ectasia.
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            The evolution of lamellar keratoplasty.

            Recent advancements in lamellar keratoplasty have two aspects: the refinement in surgical technique, which has improved postoperative visual outcomes and the transplantation of specific tissues of the donor cornea, such as limbal stem cells. Stem cell transplantation has expanded dramatically as a method of ocular surface reconstruction. Long-term prognosis for limbal allograft transplantation has recently been reported, and postoperative treatments including epithelial management and immunosuppression are now major topics to be studied.
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              Corneal ectasia as a complication of repeated keratotomy surgery.

              Staged keratotomy surgery, or "enhancement surgery," may allow a more predictable outcome, but also subjects the patient to additional surgical risks. A 39-year-old man underwent astigmatic keratotomy for myopic astigmatism, followed by 12 enhancement procedures for residual astigmatism. These procedures effectively resulted in a double hexagonal keratotomy. The patient's best spectacle-corrected acuity deteriorated to counting fingers. Clinically, a conically-shaped protrusion of the central cornea, Munson's sign, diffuse subepithelial scarring, and central corneal thinning were noted. Penetrating keratoplasty was performed. Histopathologic examination showed central thinning, epithelial edema, disruption of Bowman's layer, marked stromal scarring, and focal areas of endothelial attenuation--findings consistent with keratoconus. This case illustrates that multiple keratotomy procedures may result in corneal ectasia in apparently normal eyes and suggests that hexagonal keratotomy may be more likely to cause iatrogenic keratoconus.
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                Author and article information

                Journal
                Indian J Ophthalmol
                Indian J Ophthalmol
                IJO
                Indian Journal of Ophthalmology
                Medknow Publications & Media Pvt Ltd (India )
                0301-4738
                1998-3689
                Mar-Apr 2012
                : 60
                : 2
                : 139-141
                Affiliations
                [1]Cornea, External Disease and Refractive Surgery, Sameep Eye Hospital and Corneal Centre, Baroda, Gujarat, India
                [1 ]Cornea and Anterior Segment Services, LV Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, India
                Author notes
                Correspondence to: Dr. Somasheila Murthy, LV Prasad Eye Institute, LV Prasad Marg, Banjara Hills, Hyderabad – 500 034, India. E-mail: smurthy@ 123456lvpei.org
                Article
                IJO-60-139
                10.4103/0301-4738.94058
                3339076
                22446912
                92817c67-158e-4e8c-b1cb-dfb165f61a81
                Copyright: © Indian Journal of Ophthalmology

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 08 June 2010
                : 13 September 2011
                Categories
                Brief Communications

                Ophthalmology & Optometry
                hyperopia,corneal ectasia,hexagonal keratotomy,deep anterior lamellar keratoplasty

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