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      A sociogenomic perspective on neuroscience in organizational behavior

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          Abstract

          We critically examine the current biological models of individual organizational behavior, with particular emphasis on the roles of genetics and the brain. We demonstrate how approaches to biology in the organizational sciences assume that biological systems are simultaneously causal and essentially static; that genotypes exert constant effects. In contrast, we present a sociogenomic approach to organizational research, which could provide a meta-theoretical framework for understanding organizational behavior. Sociogenomics is an interactionist approach that derives power from its ability to explain how genes and environment operate. The key insight is that both genes and the environment operate by modifying gene expression. This leads to a conception of genetic and environmental effects that is fundamentally dynamic, rather than the static view of classical biometric approaches. We review biometric research within organizational behavior, and contrast these interpretations with a sociogenomic view. We provide a review of gene expression mechanisms that help explain the dynamism observed in individual organizational behavior, particularly factors associated with gene expression in the brain. Finally, we discuss the ethics of genomic and neuroscientific findings for practicing managers and discuss whether it is possible to practically apply these findings in management.

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          Most cited references62

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          Epigenetic programming by maternal behavior.

          Here we report that increased pup licking and grooming (LG) and arched-back nursing (ABN) by rat mothers altered the offspring epigenome at a glucocorticoid receptor (GR) gene promoter in the hippocampus. Offspring of mothers that showed high levels of LG and ABN were found to have differences in DNA methylation, as compared to offspring of 'low-LG-ABN' mothers. These differences emerged over the first week of life, were reversed with cross-fostering, persisted into adulthood and were associated with altered histone acetylation and transcription factor (NGFI-A) binding to the GR promoter. Central infusion of a histone deacetylase inhibitor removed the group differences in histone acetylation, DNA methylation, NGFI-A binding, GR expression and hypothalamic-pituitary-adrenal (HPA) responses to stress, suggesting a causal relation among epigenomic state, GR expression and the maternal effect on stress responses in the offspring. Thus we show that an epigenomic state of a gene can be established through behavioral programming, and it is potentially reversible.
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            Oxytocin, vasopressin, and the neurogenetics of sociality.

            There is growing evidence that the neuropeptides oxytocin and vasopressin modulate complex social behavior and social cognition. These ancient neuropeptides display a marked conservation in gene structure and expression, yet diversity in the genetic regulation of their receptors seems to underlie natural variation in social behavior, both between and within species. Human studies are beginning to explore the roles of these neuropeptides in social cognition and behavior and suggest that variation in the genes encoding their receptors may contribute to variation in human social behavior by altering brain function. Understanding the neurobiology and neurogenetics of social cognition and behavior has important implications, both clinically and for society.
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              Toward a structure- and process-integrated view of personality: traits as density distribution of states.

              Three experience-sampling studies explored the distributions of Big-Five-relevant states (behavior) across 2 to 3 weeks of everyday life. Within-person variability was high, such that the typical individual regularly and routinely manifested nearly all levels of all traits in his or her everyday behavior. Second, individual differences in central tendencies of behavioral distributions were almost perfectly stable. Third, amount of behavioral variability (and skew and kurtosis) were revealed as stable individual differences. Finally, amount of within-person variability in extraversion was shown to reflect individual differences in reactivity to extraversion-relevant situational cues. Thus, decontextualized and noncontingent Big-Five content is highly useful for descriptions of individuals' density distributions as wholes. Simultaneously, contextualized and contingent personality units (e.g., conditional traits, goals) are needed for describing the considerable within-person variation.
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                Author and article information

                Journal
                Front Hum Neurosci
                Front Hum Neurosci
                Front. Hum. Neurosci.
                Frontiers in Human Neuroscience
                Frontiers Media S.A.
                1662-5161
                25 February 2014
                2014
                : 8
                : 84
                Affiliations
                [1] 1School of Management, State University of New York at Binghamton Binghamton, NY, USA
                [2] 2Department of Management, University of Nebraska - Lincoln Lincoln, NE, USA
                Author notes

                Edited by: Carl Senior, Aston University, UK

                Reviewed by: Gene Robinson, University of Illinois, USA; Michael E. Price, Brunel University, UK

                *Correspondence: Seth M. Spain, School of Management, State University of New York at Binghamton, 312 Academic A, 4400 Vestal Parkway East, PO Box 6000, Binghamton, NY 13902-6000, USA e-mail: sspain@ 123456binghamton.edu

                This article was submitted to the journal Frontiers in Human Neuroscience.

                Article
                10.3389/fnhum.2014.00084
                3934417
                914835b1-af44-4c13-89f3-8797db270451
                Copyright © 2014 Spain and Harms.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 30 November 2013
                : 03 February 2014
                Page count
                Figures: 2, Tables: 0, Equations: 1, References: 111, Pages: 15, Words: 14309
                Categories
                Neuroscience
                Review Article

                Neurosciences
                behavioral genetics,epigenetics,leadership,personality,adult development,evolutionary psychology,organizational behavior

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