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      Change of inspired oxygen concentration and temperature in low flow anesthesia

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      Anesthesia and Pain Medicine
      Korean Society of Anesthesiologists

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          Abstract

          TO THE EDITOR: For low-flow anesthesia, the anesthesia workstation, monitoring technology and desflurane, sevoflurane, which were a low blood-gas partition coefficient, have gradually been adopted. Low-flow anesthesia is considered effective in maintaining the heat and the moisture of the breathing circuit and preserving the mucociliary function of the respiratory tract. In addition, it is safer and more effective at lowering the economic burden and global warming potential [1,2]. We read, with interest, your paper on “Change of inspired oxygen concentration in low flow anesthesia” (Anesth Pain Med 2020; 15: 434-40). We appreciate your results and have some questions to discuss. We have a few questions about the monitoring and the maintenance of body temperature. How did you maintain and monitor the temperature of the operating room? Was the patient's temperature measured only in the esophagus? What was the depth of the esophageal temperature probe? Depending on the room temperature and the depth of insertion, the body temperature can change with ambient influences, such as blood flow of venous return and inhaled gas temperature [3]. Therefore, the authors used a heated breathing system and a heat moisture exchanger (HME) to heat the breathing circuit. During anesthetic care, the patient’s temperature did not show a statistically significant change after 60–75 min of low flow. However, it started increasing significantly after 120 min of low flow. In this study, soda lime (CO2 absorber) and a standard circular rebreathing circuit with a heated breathing circuit were used. Did you use the HME in the heated breathing circuit? One CO2 molecule, exhaled by the patient, produces two water (H2O) molecules and generates approximately 40°C of heat during its reaction with soda lime. The moisture and heat generated by the reaction are sufficient for the patient's humidification and warmth during anesthesia 30 min after induction [1,4]. Therefore, if a low-flow system is used, there is no reason to use a heated breathing circuit and HME, sufficient heat and moisture can be maintained without a heated breathing circuit and HME [1–5]. We think that the increased temperature within the circuit is not an advantage but a problem caused by adding the heated breathing circuit and HME during low flow rather than high flow. What do you expect to get if you do not attach either of or both the heating breathing circuit and HME?

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          Most cited references5

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          Monitoring and thermal management.

          Anaesthesia alters normal thermoregulatory control of the body, usually leading to perioperative hypothermia. Hypothermia is associated with a large number of serious complications. To assess perianaesthetic hypothermia, core temperature should be monitored vigorously. Pulmonary artery, tympanic membrane, distal oesophageal or nasopharyngeal temperatures reflect core temperature reliably. Core temperatures can be often estimated with reasonable accuracy using oral, axillary and bladder temperatures, except during extreme thermal perturbations. The body site for measurements should be chosen according to the surgical procedure. Unless hypothermia is specifically indicated, efforts should be made to maintain intraoperative core temperatures above 36 degrees C. Forced air is the most effective, commonly available, non-invasive warming method. Resistive heating electrical blankets and circulating water garment systems are an equally effective alternative. Intravenous fluid warming is also helpful when large volumes are required. In some patients, induction of mild therapeutic hypothermia may become an issue for the future. Recent studies indicate that patients suffering from neurological disease may profit from rapid core cooling.
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            Low-flow anaesthesia

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              Low and minimal flow inhalational anaesthesia.

              To describe the pharmacokinetic behaviour and practical aspects of low (0.5-1 l.min-1) and minimal (0.25-0.5 l.min-1) flow anaesthesia. A Medline search located articles on low flow anaesthesia, and computer simulated anaesthetic uptake models are used. Most, 85-90%, of anaesthetists use high fresh gas flow rates during inhalational anaesthesia. Low/minimal flow anaesthesia with a circle circuit may avoid the need for in-circuit humidifiers, raise the temperature of inspired gases by up to 6 degrees C, reduce cost by about 25% by reduction of fresh gas flows to 1.5 l.min-1, and reduce environmental pollution with scavenged gas. Knowledge of volatile anaesthetic pharmacokinetic behaviour facilitates the use of minimal/low flow rates. Small amounts of nitrogen or minute amounts of methane, acetone, carbon monoxide, and inert gases in the circuit are of no concern, but the degradation of desflurane (to carbon monoxide by dry absorbent) and sevoflurane (to compound A by using a fresh gas flow of > 2 l.min-1) must be avoided. With modern gas monitoring technology, safety should be no more of a concern than with high flow techniques. The use of fresh gas flow rates of < 1 l.min-1 for maintenance of anaesthesia has many advantages, and should be encouraged for inhalational anaesthesia with most modern volatile anaesthetics.
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                Author and article information

                Journal
                Anesth Pain Med (Seoul)
                Anesth Pain Med (Seoul)
                APM
                Anesthesia and Pain Medicine
                Korean Society of Anesthesiologists
                1975-5171
                2383-7977
                31 January 2021
                27 January 2021
                : 16
                : 1
                : 116-117
                Affiliations
                Department of Anesthesiology and Pain Medicine, Daejeon Eulji Medical Center, Medical College, Eulji University, Daejeon, Korea
                Author notes
                Corresponding Author: Hong Seuk Yang, M.D., Ph.D. Department of Anesthesiology and Pain Medicine, Daejeon Eulji Medical Center, Medical College, Eulji University, 95 Dunsanseo-ro, Seo-gu, Daejeon 35233, Korea Tel: 82-42-611-3883, Fax: 82-42-259-1111 E-mail: hsyang@ 123456amc.seoul.kr
                Author information
                http://orcid.org/0000-0003-2023-8705
                http://orcid.org/0000-0002-6587-3756
                http://orcid.org/0000-0002-8830-3406
                Article
                apm-20095
                10.17085/apm.20095
                7861906
                33530680
                911681fb-c32d-4a7f-bfda-2b47be09d434
                Copyright © the Korean Society of Anesthesiologists, 2021

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 8 December 2020
                : 13 January 2021
                Categories
                Letter to the Editor

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