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Symptom interval and treatment burden for patients with malignant central nervous system germ cell tumours.

Author(s): James Hayden, Matthew Murray, Ute Bartels, Thankamma Ajithkumar, Brinda Muthusamy, Anthony Penn, Gabriele Calaminus, James Nicholson

Publication date: 2020-03-01

Journal: Archives of Disease in Childhood

Publisher: BMJ

Keywords: Outcomes research, brain tumour, prolonged symptom interval, symptom interval, intervention

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Abstract

Patients with central nervous system germ cell tumours (CNS-GCTs) commonly initially present to primary care or general paediatricians. Prolonged symptom intervals (SI) are frequently seen in CNS-GCTs and have been associated with inferior outcomes in other brain tumours. This study reviewed the clinical presentation of CNS-GCTs and examined the effect of prolonged SI.

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PubMed ID:: 31594777

DOI:: 10.1136/archdischild-2019-317245

Keywords: Outcomes research,brain tumour,prolonged symptom interval,symptom interval,intervention

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Keywords: Outcomes research, brain tumour, prolonged symptom interval, symptom interval, intervention

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