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      3D Super-Resolution Optical Profiling Using Microsphere Enhanced Mirau Interferometry

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          Abstract

          We present quantitative three dimensional images of grooves on a writable Blu-ray Disc based on a single objective Mirau type interferometric microscope, enhanced with a microsphere which is considered as a photonic nanojet source. Along the optical axis the resolution of this microsphere assisted interferometry system is a few nanometers while the lateral resolution is around 112 nm. To understand the physical phenomena involved in this kind of imaging we have modelled the interaction between the photonic jet and the complex disc surface. Agreement between simulation and experimental results is demonstrated. We underline that although the ability of the microsphere to generate a photonic nanojet does not alone explain the resolution of the interferometer, the nanojet can be used to try to understand the imaging process. To partly explain the lateral super-resolution, the potential role of coherence is illustrated. The presented modality may have a large impact on many fields from bio-medicine to nanotechnology.

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          Most cited references15

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          Label-free super-resolution imaging of adenoviruses by submerged microsphere optical nanoscopy

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            The optical microscopy with virtual image breaks a record: 50-nm resolution imaging is demonstrated

            We demonstrate a new 'microsphere nanoscope' that uses ordinary SiO2 microspheres as superlenses to create a virtual image of the object in near field. The magnified virtual image greatly overcomes the diffraction limit. We are able to resolve clearly 50-nm objects under a standard white light source in both transmission and reflection modes. The resolution achieved for white light opens a new opportunity to image viruses, DNA and molecules in real time.
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              Optical super-resolution by high-index liquid-immersed microspheres

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                Author and article information

                Contributors
                ivan.kassamakov@helsinki.fi
                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group UK (London )
                2045-2322
                16 June 2017
                16 June 2017
                2017
                : 7
                : 3683
                Affiliations
                [1 ]ISNI 0000 0004 0410 2071, GRID grid.7737.4, , University of Helsinki, ; Helsinki, Finland
                [2 ]ISNI 0000 0001 2157 9291, GRID grid.11843.3f, ICube Laboratory, , University of Strasbourg-CNRS, ; Strasbourg, France
                Article
                3830
                10.1038/s41598-017-03830-6
                5473836
                28623289
                90b1a764-8ffd-4cef-a113-1379da81126a
                © The Author(s) 2017

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 21 October 2016
                : 5 May 2017
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