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Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease.

Author(s): Andrea Richardson, A B Onderdonk, Rachel R. Hammer, J Taurog

Publication date: 1998-11-30

Keywords: Animals, Animals, Genetically Modified, Cecum, microbiology, Enterococcus, isolation & purification, Escherichia coli, Female, HLA-B27 Antigen, biosynthesis, genetics, Inflammatory Bowel Diseases, Male, Rats

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Abstract

Transgenic rats with a high level of expression of the human major histocompatibility complex class I molecule HLA-B27 develop chronic inflammatory bowel disease (IBD) and arthritis. Assessment of the cecal microflora showed a rise in numbers of Escherichia coli and Enterococcus spp., corresponding to the presence and severity of IBD in these rats.

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PubMed ID:: 9826389

PMC ID:: 108765

DOI:: 10.1128/IAI.66.12.6022-6023.1998

ScienceOpen disciplines: Chemistry

Keywords: Animals,Animals, Genetically Modified,Cecum,microbiology,Enterococcus,isolation & purification,Escherichia coli,Female,HLA-B27 Antigen,biosynthesis,genetics,Inflammatory Bowel Diseases,Male,Rats

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ScienceOpen disciplines: Chemistry

Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease.

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Biomarkers for Inflammatory Lung Disease

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