The year 2022 marks a century since the death of Reverend John Knox Bokwe, a minister of the United Free Church of Scotland Mission in South Africa. Although little known, Bokwe was an important member of the emerging African intellectual elite towards the end of the 19th century. He demonstrated the creative tension that arises when two cultures encounter each other as he confronted and made sense of the historical meaning of modernity. He emphasised the value of his traditional culture in a context where western culture was making a significant transforming impact on African life, which produced a creative tension throughout his working life in various contexts. This paper analyses his particular contribution as an active committed Christian through a number of overlapping lenses - his life in clerical work, journalism, literature, theology, education, music and his involvement in social and political issues and ministry. In all this he operated with a holistic vision. The paper offers an assessment of his life's work using a combination of primary and secondary sources. CONTRIBUTION: This article adds to the growing body of work that is derived from studies on the emergence of indigenous leadership in South Africa by looking at the life, work and Christian witness of Rev John Knox Bokwe from the perspective of the creative tension that he experienced and navigated in the varied professional and vocational perspectives he engaged in during his life