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      Bone Cement-Augmented Percutaneous Short Segment Fixation: An Effective Treatment for Kummell's Disease?

      research-article
      , Ph.D. 1 , , M.D., Ph.D. 2 , , M.D., Ph.D. 3 , , M.D., Ph.D. 4 ,
      Journal of Korean Neurosurgical Society
      The Korean Neurosurgical Society
      Osteonecrosis, Screw, Cement

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          Abstract

          Objective

          The aim of this prospective study was to evaluate the efficacy of bone cement-augmented percutaneous short segment fixation for treating Kummell's disease accompanied by severe osteoporosis.

          Methods

          From 2009 to 2013, ten patients with single-level Kummell's disease accompanied by severe osteoporosis were enrolled in this study. After postural reduction for 1-2 days, bone cement-augmented percutaneous short segment fixation was performed at one level above, one level below, and at the collapsed vertebra. Clinical results, radiological parameters, and related complications were assessed preoperatively and at 1 month and 12 months after surgery.

          Results

          Prior to surgery, the mean pain score on the visual analogue scale was 8.5±1.5. One month after the procedure, this score improved to 2.2±2.0 and the improvement was maintained at 12 months after surgery. The mean preoperative vertebral height loss was 48.2±10.5%, and the surgical procedure reduced this loss to 22.5±12.4%. In spite of some recurrent height loss, significant improvement was achieved at 12 months after surgery compared to preoperative values. The kyphotic angle improved significantly from 22.4±4.9° before the procedure to 10.1±3.8° after surgery and the improved angle was maintained at 12 months after surgery despite a slight correction loss. No patient sustained adjacent fractures after bone cement-augmented percutaneous short segment fixation during the follow-up period. Asymptomatic cement leakage into the paravertebral area was observed in one patient, but no major complications were seen.

          Conclusion

          Bone cement-augmented percutaneous short segment fixation can be an effective and safe procedure for Kummell's disease.

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          Most cited references15

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          Recollapse of previous vertebral compression fracture after percutaneous vertebroplasty.

          This study was undertaken to investigate the incidence rate, characteristics, and predisposing factors associated with recollapse of the same vertebrae after percutaneous vertebroplasty (PVP). Recollapse of the same vertebra after PVP is the one of the complications of the procedure, and the incidence rate in our study was 3.21%. The most important predisposing factor was pre-operative osteonecrosis. Recollapse was not related to trauma. PVP using polymethylmethacrylate has become a popular treatment for osteoporotic vertebral compression fracture. Recollapse of the same vertebrae after PVP has rarely been reported. This study was undertaken to investigate the incidence, characteristics, and predisposing factors associated with recollapse of the same vertebrae after PVP. Eleven patients (seven females and four males; mean age, 69.91 +/- 5.49 years), out of a total of 343 patients, developed recollapse of the same vertebra after PVP. The 11 patients who developed recollapse comprised the "recollapse group", while the remaining 332 patients comprised the "well-maintained group". Pre-operative magnetic resonance imaging revealed that the incidence of osteonecrosis was significantly higher in the recollapse group than the well-maintained group (p < 0.05). The degree of re-expansion of the compressed vertebral body after PVP was significantly higher in the recollapse group than in the well-maintained group (p < 0.05). The most important predisposing factor for recollapse was pre-operative osteonecrosis. Recollapse was not related to trauma. Osteoporotic vertebral compression fracture with osteonecrosis or pseudoarthrosis has been regarded as a relative indication for PVP; however, the findings of this study suggest that this disease category may be a relative contraindication for PVP.
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            Anterior-posterior surgery versus posterior closing wedge osteotomy in posttraumatic kyphosis with neurologic compromised osteoporotic fracture.

            Retrospective study. To compare the surgical results between combined anterior-posterior procedures and posterior closing wedge osteotomy procedures in patients with posttraumatic kyphosis and neurologic compromise secondary to osteoporotic fractures. Combined anterior-posterior procedures are usually recommended in cases of kyphotic deformities with neurologic deficit secondary to osteoporosis. However, combined anterior-posterior surgery is associated with significant morbidity in elderly patients. Twenty-six patients with posttraumatic kyphosis and neurologic compromise secondary to osteoporotic fracture were indicated for operative intervention using either a combined anterior-posterior surgery (n = 11) or a posterior closing wedge osteotomy procedure (n = 15). The results of the two procedures were analyzed. The average patient age at the operation was 62.6 years (range: 50-82) with a 12:14 male-to-female ratio. Mean follow-up was 3.5 years (range: 2.1-5.4). Preoperative interval from injury to operation was 15.4 months (range: 1-36). There were 20 thoracolumbar (T12-L1) fractures and six lumbar fractures indicated for operative intervention. In the combined anterior-posterior group, the mean operative time was 351 minutes with a mean blood loss of 2,892 mL. In the posterior closing wedge osteotomy group, the mean operative time was 215 minutes with blood loss of 1,930 mL. Eighteen patients showed a postoperative improvement in Frankel grading, 64% (7/11) in the combined anterior-posterior group, and 73% (11/15) in posterior closing wedge osteotomy group. There were no neurologic or vascular complications in either group. In the combined anterior-posterior group, there were five complications: two postoperative pneumonias, one superficial infection, and two distal screw loosening. There were only two complications in the posterior closing wedge osteotomy group: two distal screw loosening. One of the four cases of distal screw loosening required surgical revision. The other three cases were treated by bracing for more than 6 months. Although technically demanding, the posterior closing wedge osteotomy procedure demonstrated a better surgical result with significant less mean operative time and mean blood loss (P < 0.05). It may be a better alternative than a combined anterior-posterior procedure in patients with posttraumatic kyphosis and neurologic compromise secondary to osteoporotic fracture.
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              Efficacy of percutaneous vertebroplasty in the treatment of intravertebral pseudarthrosis associated with noninfected avascular necrosis of the vertebral body.

              A retrospective clinical study on the effect of percutaneous vertebroplasty (PVP) in the treatment of intravertebral pseudarthrosis caused by avascular necrosis of a vertebral body. To evaluate the efficacy of PVP in the treatment of spinal instability associated with avascular necrosis. Two radiologic features of avascular necrosis of a vertebral body are intravertebral vacuum phenomenon and fluid collection, combined with a collapsed vertebra. These can sometimes result in dynamic instability due to intravertebral pseudarthrosis. A treatment for this instability, associated with avascular necrosis, has not been established. Sixteen patients with instability, associated with avascular necrosis of a vertebral body, were treated by PVP. The indicators of the condition included spinal instability associated with avascular necrosis, which was diagnosed by a vacuum phenomenon or by fluid collection in the vertebral body as found from imaging studies. The instability of the vertebral body was confirmed from the dynamic lateral view in both flexion and extension. The anterior body height and kyphotic angle changes between pre- and post-treatment were measured on a lateral radiograph. Plain radiography was used during the follow-up period (8-14 months; mean, 11 months) to assess the vertebral column stability. The pain level of each patient was assessed, both before and after the procedure, using a visual analog scale (VAS), ranging from 0 to 10. Marked or complete pain relief was achieved in eight (50%) patients, and moderate pain relief in six (38%), with the immediate postoperative average pain score reduced from 9.0 to 4.3. The mean corrected angle and vertebral height between pre- and post-treatment were 8.5 degrees and 7.0 mm (P =0.001), respectively. There was no significant change in the kyphotic angle of the treated level during the follow-up period (P =0.711). Percutaneous vertebroplasty is a reasonable procedure for the treatment of spinal instability associated with avascular necrosis, but not that caused by an infection. PVP was found to be a minimally invasive and effective procedure that provides pain relief and stabilization of spinal instability associated with noninfected avascular necrosis of the vertebral body.
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                Author and article information

                Journal
                J Korean Neurosurg Soc
                J Korean Neurosurg Soc
                JKNS
                Journal of Korean Neurosurgical Society
                The Korean Neurosurgical Society
                2005-3711
                1598-7876
                July 2015
                31 July 2015
                : 58
                : 1
                : 54-59
                Affiliations
                [1 ]Department of Natural Medical Sciences, College of Health Science, Chosun University, Gwangju, Korea.
                [2 ]Department of Neurosurgery, Sun Han Hospital, Gwangju, Korea.
                [3 ]Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chosun University, Gwangju, Korea.
                [4 ]Department of Neurosurgery, College of Medicine, Chosun University, Gwangju, Korea.
                Author notes
                Address for reprints: Seok Won Kim, M.D., Ph.D. Department of Neurosurgery, College of Medicine, Chosun University, 365 Pilmun-daero, Dong-gu, Gwangju 501-717, Korea. Tel: +82-62-220-3126, Fax: +82-62-227-4575, chosunns@ 123456chosun.ac.kr
                Article
                10.3340/jkns.2015.58.1.54
                4534740
                26279814
                8fa30438-1f8b-472d-9b02-cc609d90eb5b
                Copyright © 2015 The Korean Neurosurgical Society

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 04 December 2014
                : 24 March 2015
                : 22 April 2015
                Categories
                Clinical Article

                Surgery
                osteonecrosis,screw,cement
                Surgery
                osteonecrosis, screw, cement

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