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      Big Data Research in the Field of Endocrine Diseases Using the Korean National Health Information Database

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          Abstract

          The Korean National Health Information Database (NHID) contains big data combining information obtained from the National Health Insurance Service and health examinations. Data are provided in the form of a cohort, and the NHID can be used to conduct longitudinal studies and research on rare diseases. Moreover, data on the cause and date of death are provided by Statistics Korea. Research and publications based on the NHID have increased explosively in the field of endocrine disorders. However, because the data were not collected for research purposes, studies using the NHID have limitations, particularly the need for the operational definition of diseases. In this review, we describe the characteristics of the Korean NHID, operational definitions of endocrine diseases used for research, and an overview of recent studies in endocrinology using the Korean NHID.

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          9. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes-2023.

          Nuha A ElSayed, Grazia Aleppo, Vanita R Aroda … (2023)
          The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
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            Cardiovascular Research Using the Korean National Health Information Database

            Eue-Keun Choi (2020)
            The Korean National Health Information Database (NHID) contains nationwide claims data, including sociodemographic data, health care utilization, health screening data, and healthcare provider information. To compensate for the limitations of randomized clinical trials, real-world observational studies using claims data have emerged as a novel research tool. We summarized the structure of the Korean NHID and the recent researches conducted in the field of cardiovascular science. Epidemiological studies, prescription patterns, temporal trends, comparison of effectiveness and safety of treatments, variability index using laboratory data, and rare intractable disease constitute interesting topics of research in cardiovascular science using the NHID. The operational definition of covariates and clinical outcomes is important for researchers interested in using the NHID data as new tools to prove their hypothesis. A step-by-step approach adopted by a team of data scientists, epidemiologists, statisticians, and clinical researchers may be most effective while designing research studies. The ultimate direction of research using the NHID should aim to improve the welfare of the public by promoting public health, reducing medical costs, and guiding healthcare policies.
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              2020 Korean Society for the Study of Obesity Guidelines for the Management of Obesity in Korea

              Bo-Yeon Kim, Seon Mee Kang, Jee-Hyun Kang … (2021)
              Obesity is a prevalent and complex disease. The prevalence of obesity in Korea increased from 29.7% in 2010 to 35.7% in 2018, with the prevalence of abdominal obesity being 23.8% in 2018. Obesity contributes to medical costs and socioeconomic burden due to associated comorbidities. The treatment and management of obesity is changing based on new clinical evidence. The 2020 Korean Society for the Study of Obesity Guideline for the Management of Obesity in Korea summarizes evidence-based recommendations and treatment guidelines.
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                Author and article information

                Journal
                Journal ID (nlm-ta): Endocrinol Metab (Seoul)
                Journal ID (iso-abbrev): Endocrinol Metab (Seoul)
                Journal ID (publisher-id): ENM
                Title: Endocrinology and Metabolism
                Publisher: Korean Endocrine Society
                ISSN (Print): 2093-596X
                ISSN (Electronic): 2093-5978
                Publication date (Print): February 2023
                Publication date (Electronic): 9 February 2023
                Volume: 38
                Issue: 1
                Pages: 10-24
                Affiliations
                [1 ]Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
                [2 ]Division of Endocrinology and Metabolism, Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea
                [3 ]Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
                [4 ]Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Korea
                [5 ]Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
                Author notes
                Corresponding authors: Mee Kyoung Kim. Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 10 63-ro, Yeongdeungpo-gu, Seoul 07345, Korea Tel: +82-2-3779-1368, Fax: +82-2-595-2534, E-mail: makung@ 123456catholic.ac.kr
                Eun Jung Rhee. Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Korea Tel: +82-2-2001-2485, Fax: +82-2-2001-1588, E-mail: hongsiri@ 123456hanmail.net
                [*]

                These authors contributed equally to this work.

                Author information
                http://orcid.org/0000-0002-7394-3830
                http://orcid.org/0000-0003-1932-0234
                http://orcid.org/0000-0002-6506-4342
                http://orcid.org/0000-0003-3205-9114
                http://orcid.org/0000-0002-6108-7758
                Article
                Publisher ID: enm-2023-102
                DOI: 10.3803/EnM.2023.102
                PMC ID: 10008661
                PubMed ID: 36758542
                SO-VID: 8f768bca-c4c0-46a7-8d83-27f9e2af17c5
                Copyright © Copyright © 2023 Korean Endocrine Society
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 19 January 2023
                Date revision received : 26 January 2023
                Date accepted : 31 January 2023
                Categories
                Subject: Review Article
                Subject: Diabetes, Obesity and Metabolism

                Keywords: databases, factual,endocrine system diseases,thyroid diseases,obesity,osteoporosis,republic of korea
                Data availability:
                Keywords: databases, factual, endocrine system diseases, thyroid diseases, obesity, osteoporosis, republic of korea

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