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      Complications of Medium Depth and Deep Chemical Peels

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          Abstract

          Superficial and medium depth peels are dynamic tools when used as part of office procedures for treatment of acne, pigmentation disorders, and photo-aging. Results and complications are generally related to the depth of wounding, with deeper peels providing more marked results and higher incidence of complications. Complications are also more likely with darker skin types, certain peeling agents, and sun exposure. They can range from minor irritations, uneven pigmentation to permanent scarring. In very rare cases, complications can be life-threatening.

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          Chemical peels in aesthetic dermatology: an update 2009.

          E Perosino, Gisely Viera, F Poli … (2010)
          Peelings are among the oldest and most widespread aesthetic procedures used in aesthetic dermatology worldwide. More than 50 commercial peelings are currently available on the European market. In the present review, we summarise the current knowledge on chemical peels. A state-of-the-art peeling procedure will take into account the depth of the targeted structure and the skin condition of the patient to choose carefully among the variables such as chemical class of the peeling agent, concentration, frequency and pressure of the application. The usual classification of chemical peels comprises superficial, medium and deep peels. For superficial peels alpha-hydroxy-acids and most recently lipo-hydroxy acid are used to induce an exfoliation of the epidermis. Medium-depth agents such as trichloroacetic acid ( 50%) or phenol based formulations reach the reticular dermis to induce dermal regeneration. The success of any peel is crucially dependent on the physicians understanding of the chemical and biological processes, as well as of indications, clinical effectiveness and side effects of the procedures.
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            Oral isotretinoin as part of the treatment of cutaneous aging.

            T. Alvarez, E. Perez Codina, H Khawaja (2000)
            A number of drugs have been used to prevent aging changes. However, studies of oral isotretinoin, the commonly used acne drug, as an antiaging drug are lacking. To determine improvement in cutaneous aging utilizing oral isotretinoin combined with different procedures of facial rejuvenation. Sixty patients ranging in age from 35 to 65 years, in whom additional modalities of rejuvenation were also used, were randomly assigned to receive treatment with oral isotretinoin (10-20 mg three times a week for 2 months, group A). Their results were compared with 60 patients who had undergone the same surgical procedures but with no oral isotretinoin (group B). All patients treated with oral isotretinoin noted improvement in wrinkles, thickness and color of the skin, size of pores, skin elasticity, tone, and reduction in pigmented lesions and mottled hyperpigmentation. A statistically significant difference was found in the improvement of group A (Wilcoxon test <0.01). Using minimal amounts of this drug, the side effects were practically negligible. Utilizing various procedures with oral isotretinoin allowed us to improve the effects of cutaneous aging. Our results using isotretinoin in these cases have been satisfactory. We believe that this is one of the first reports of the use of oral isotretinoin in intrinsic and photoaged skin.
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              A history of chemical peeling.

              Gene Brody, Gary Monheit, Charles S Resnik … (2000)
              Article 0 comments Cited 9 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): J Cutan Aesthet Surg
                Journal ID (iso-abbrev): J Cutan Aesthet Surg
                Journal ID (publisher-id): JCAS
                Title: Journal of Cutaneous and Aesthetic Surgery
                Publisher: Medknow Publications & Media Pvt Ltd (India )
                ISSN (Print): 0974-2077
                ISSN (Electronic): 0974-5157
                Publication date (Print): Oct-Dec 2012
                Volume: 5
                Issue: 4
                Pages: 254-260
                Affiliations
                [1] Dr. D. Y. Patil Medical College, Navi Mumbai, Maharashtra, India
                [1 ] Sakhiya Skin Clinic, Surat, Gujarat, India
                Author notes
                Address for correspondence: Dr. Nanma Nikalji, 54 OPD, Skin OPD, 1 st Floor, Dr. D. Y. Patil Hospital, Nerul, Mumbai, India. E-mail: drnanma@ 123456gmail.com
                Article
                Publisher ID: JCAS-5-254
                DOI: 10.4103/0974-2077.104913
                PMC ID: 3560165
                PubMed ID: 23378707
                SO-VID: 8d3120ab-196b-4459-8356-f55e2e5586e0
                Copyright © Copyright: © Journal of Cutaneous and Aesthetic Surgery
                License:

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Categories
                Subject: CME

                ScienceOpen disciplines: Surgery
                Keywords: chemical peel,superficial and medium depth,complications
                Data availability:
                ScienceOpen disciplines: Surgery
                Keywords: chemical peel, superficial and medium depth, complications

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