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      Comparative efficacy and tolerability of pharmacological treatments in the maintenance treatment of bipolar disorder: a systematic review and network meta-analysis.

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          Abstract

          Lithium is the established standard in the long-term treatment of bipolar disorder, but several new drugs have been assessed for this indication. We did a network meta-analysis to investigate the comparative efficacy and tolerability of available pharmacological treatment strategies for bipolar disorder.

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          Author and article information

          Journal
          Lancet Psychiatry
          The lancet. Psychiatry
          2215-0374
          2215-0366
          Oct 2014
          : 1
          : 5
          Affiliations
          [1 ] Department of Neuropsychiatry Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. Electronic address: tmiura@npsych.med.kyushu-u.ac.jp.
          [2 ] Department of Data Science, The Institute of Statistical Mathematics, Tokyo, Japan.
          [3 ] Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine and School of Public Health, Kyoto, Japan.
          [4 ] Department of Neuropsychiatry Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
          [5 ] Department of Pharmacoepidemiology, Kyoto University School of Public Health, Kyoto, Japan.
          [6 ] Department of Psychiatry, University of Oxford, Oxford, UK.
          [7 ] Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.
          [8 ] Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.
          [9 ] Department of Psychiatry, University of Oxford, Oxford, UK; Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy.
          Article
          S2215-0366(14)70314-1
          10.1016/S2215-0366(14)70314-1
          26360999
          8988fb72-f8d9-4918-800e-75bb51983125
          Copyright © 2014 Elsevier Ltd. All rights reserved.
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