Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa.

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Abstract

Hidradenitis suppurativa is a painful, chronic inflammatory skin disease with few options for effective treatment. In a phase 2 trial, adalimumab, an antibody against tumor necrosis factor α, showed efficacy against hidradenitis suppurativa.

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Journal

Journal ID (iso-abbrev): N. Engl. J. Med.

Title: The New England journal of medicine

Publisher: New England Journal of Medicine (NEJM/MMS)

ISSN (Electronic): 1533-4406

ISSN (Print): 0028-4793

Publication date (Electronic): Aug 04 2016

Volume: 375

Issue: 5

Affiliations

[1 ] From Harvard Medical School and Massachusetts General Hospital (A.B.K.) and Tufts Medical Center (A.B.G.) - all in Boston; AbbVie, North Chicago, IL (M.M.O., D.A.W., E.A., N.M.M., B.P., M.S., Y.G., D.M.C.); Probity Medical Research and K Papp Clinical Research, Waterloo, ON (K.A.P.), and the Lynde Centre for Dermatology and Probity Medical Research, Markham, ON (C.L.) - both in Canada; the Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Dessau, Germany (C.C.Z.); University of Southern California, Los Angeles (A.W.A.), and Bakersfield Dermatology, Bakersfield (J.J.C.) - both in California; Florida Academic Dermatology Centers, Miami (F.K.), and Forward Clinical Trials, Tampa (S.B.F.) - both in Florida; Tennessee Clinical Research Center, Nashville (M.H.G.); University Hospitals Case Medical Center, Cleveland (N.J.K.); 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens (E.J.G.-B.); CHU de Reims, Hôpital Robert Debré, Service de Dermatologie, Reims, France (Z.R.); Erasmus University Medical Center, Rotterdam, the Netherlands (E.-P.P.); and the Department of Dermatology, Roskilde Hospital, and Health Sciences Faculty, University of Copenhagen, Copenhagen (G.B.E.J.).

Article

DOI: 10.1056/NEJMoa1504370

PubMed ID: 27518661

SO-VID: 88d3c375-a0c2-49c2-bcd2-63eaff36aa55

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