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Oestrogenic potency of genistin and daidzin in mice
August 1985
August 1985
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Abstract
The oestrogenic activity of genistin and daidzin was investigated in the B6D2F1 strain
of mouse. Diethylstilboestrol and genistein were used as positive controls. The oestrogenic
response to 1.5 mg genistin was equivalent to that of 1 mg genistein, giving a 1:1
molar relationship in oestrogenic activity between genistin and genistein. The oestrogenic
response to 3.8 mg daidzin was equivalent to that of 1 mg genistein. Analysis of the
blood obtained from the mice in this experiment failed to reveal any free genistein
or daidzein in the plasma.