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      Atividade in vitro de permetrina, cipermetrina e deltametrina sobre larvas de Rhipicephalus sanguineus (Latreille, 1806) (Acari, Ixodidae) Translated title: In vitro activity of permethrin, cipermethrin and deltamethrin on larvae of Rhipicephalus sanguineus (Latreille, 1806) (Acari, Ixodidae)

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          Abstract

          Investigaram-se os efeitos toxicológicos in vitro de três piretróides em diferentes concentrações, formulados para uso pecuário, domiciliar e em cães, sobre larvas de R. sanguineus, objetivando monitorar sua suscetibilidade e fomentar seu controle. Utilizaram-se 1.604 larvas em jejum, com 15 a 21 dias, obtidas por infestação artificial em cão, imersas nas soluções testadas, contidas em dispositivos constituídos por placa de Petri descartável, papel filtro e parafina, mantidas em incubadoras do tipo BOD e observadas ao estereoscópio por 24h. Observaram-se excitabilidade, movimentação repetitiva, diminuição da locomoção, desprendimento, paralisia, "knock-down" e proliferação cuticular de gases e líquidos. A mortalidade na 24ª hora foi de 86,9%, 100,0%, 80,3%, 86,0%, 68,2% e 78,0%, respectivamente, para permetrina 1250ppm e 2500ppm, cipermetrina 150ppm e 300ppm, e deltametrina 25ppm e 50ppm. Não houve mortalidade no grupo controle.

          Translated abstract

          Aiming at monitoring the susceptibility, increasing the control and evaluating the toxicological effects, of different concentrations of three pyrethroids were investigated in vitro against Rhipicephalus sanguineus larvae using concentrations formulated for cattle, dogs and household use. A total of 1,604 15-21 day-old fasting larvae, obtained by artificial infestation in dogs, was immersed in the solutions. Larvae were then maintained in BOD incubators inside experimental devices, constituted by disposable Petridishes, filter paper and paraffin, and observed on the stereomicroscope during a 24-hour period. The larvae have shown excitability, repetitive movements, decrease of locomotion, detachment, paralysis, knock-down and production of gases and liquid in the cuticle. Mortality after 24 hours was 86.9% (1250ppm) and 100.0% (2500ppm) for permethrin; 80.3% (150ppm) and 86.0% (300ppm) for cipermethrin; and for deltamethrin 68.2% (25ppm) and 78.0% (50ppm). Mortality was not observed in the control group.

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            Cell death in the regulation of immune responses.

            Cell death is an integral part of the functioning of the immune system. For T cells, potentially autoreactive or 'useless' cells are removed through apoptosis in response to signals (or lack of signals) from their T cell receptor complex. A myriad of proteins that can initiate or protect cells from cell death have recently been identified.
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              Vector resistance to pesticides

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                Author and article information

                Contributors
                Role: ND
                Journal
                abmvz
                Arquivo Brasileiro de Medicina Veterinária e Zootecnia
                Arq. Bras. Med. Vet. Zootec.
                Universidade Federal de Minas Gerais, Escola de Veterinária (Belo Horizonte )
                1678-4162
                December 2000
                : 52
                : 6
                : 621-626
                Affiliations
                [1 ] Universidade Federal de Goiás Brazil
                Article
                S0102-09352000000600012
                10.1590/S0102-09352000000600012
                86fd62f9-f916-4e1b-ab53-b5b48beb7ebe

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Brazil

                Self URI (journal page): http://www.scielo.br/scielo.php?script=sci_serial&pid=0102-0935&lng=en
                Categories
                VETERINARY SCIENCES

                General veterinary medicine
                Tick,Rhipicephalus sanguineus,pyrethroid,Carrapato,piretróide
                General veterinary medicine
                Tick, Rhipicephalus sanguineus, pyrethroid, Carrapato, piretróide

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