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Abstract
Objectives
In this review, we aim to highlight the evidence base for the benefits of exercise
in relation to the treatment of noncommunicable diseases (NCDs), draw on the Health
Triangular Policy Framework to outline the principal facilitators and barriers for
implementing exercise in health policy, and make concrete suggestions for action.
Methods
Literature review and framework analysis were conducted to deal with the research
questions.
Results
Exercise prescription is a safe solution for noncommunicable diseases prevention and
treatment that enables physicians to provide and instruct patients how to apply exercise
as an important aspect of disease treatment and management. Combining exercise prescription
within routine care, in inpatient and outpatient settings, will improve patients’
life quality and fitness levels.
Conclusion
Inserting exercise prescription into the healthcare system would improve population
health status and healthy lifestyles. The suggestions outlined in this study need
combined efforts from the medical profession, governments, and policymakers to facilitate
practice into reality in the healthcare arena.
This review provides the reader with the up-to-date evidence-based basis for prescribing exercise as medicine in the treatment of 26 different diseases: psychiatric diseases (depression, anxiety, stress, schizophrenia); neurological diseases (dementia, Parkinson's disease, multiple sclerosis); metabolic diseases (obesity, hyperlipidemia, metabolic syndrome, polycystic ovarian syndrome, type 2 diabetes, type 1 diabetes); cardiovascular diseases (hypertension, coronary heart disease, heart failure, cerebral apoplexy, and claudication intermittent); pulmonary diseases (chronic obstructive pulmonary disease, asthma, cystic fibrosis); musculo-skeletal disorders (osteoarthritis, osteoporosis, back pain, rheumatoid arthritis); and cancer. The effect of exercise therapy on disease pathogenesis and symptoms are given and the possible mechanisms of action are discussed. We have interpreted the scientific literature and for each disease, we provide the reader with our best advice regarding the optimal type and dose for prescription of exercise.
The third UN High-Level Meeting on Non-Communicable Diseases (NCDs) on Sept 27, 2018, will review national and global progress towards the prevention and control of NCDs, and provide an opportunity to renew, reinforce, and enhance commitments to reduce their burden. NCD Countdown 2030 is an independent collaboration to inform policies that aim to reduce the worldwide burden of NCDs, and to ensure accountability towards this aim. In 2016, an estimated 40·5 million (71%) of the 56·9 million worldwide deaths were from NCDs. Of these, an estimated 1·7 million (4% of NCD deaths) occurred in people younger than 30 years of age, 15·2 million (38%) in people aged between 30 years and 70 years, and 23·6 million (58%) in people aged 70 years and older. An estimated 32·2 million NCD deaths (80%) were due to cancers, cardiovascular diseases, chronic respiratory diseases, and diabetes, and another 8·3 million (20%) were from other NCDs. Women in 164 (88%) and men in 165 (89%) of 186 countries and territories had a higher probability of dying before 70 years of age from an NCD than from communicable, maternal, perinatal, and nutritional conditions combined. Globally, the lowest risks of NCD mortality in 2016 were seen in high-income countries in Asia-Pacific, western Europe, and Australasia, and in Canada. The highest risks of dying from NCDs were observed in low-income and middle-income countries, especially in sub-Saharan Africa, and, for men, in central Asia and eastern Europe. Sustainable Development Goal (SDG) target 3.4-a one-third reduction, relative to 2015 levels, in the probability of dying between 30 years and 70 years of age from cancers, cardiovascular diseases, chronic respiratory diseases, and diabetes by 2030-will be achieved in 35 countries (19%) for women, and 30 (16%) for men, if these countries maintain or surpass their 2010-2016 rate of decline in NCD mortality. Most of these are high-income countries with already-low NCD mortality, and countries in central and eastern Europe. An additional 50 (27%) countries for women and 35 (19%) for men are projected to achieve such a reduction in the subsequent decade, and thus, with slight acceleration of decline, could meet the 2030 target. 86 (46%) countries for women and 97 (52%) for men need implementation of policies that substantially increase the rates of decline. Mortality from the four NCDs included in SDG target 3.4 has stagnated or increased since 2010 among women in 15 (8%) countries and men in 24 (13%) countries. NCDs and age groups other than those included in the SDG target 3.4 are responsible for a higher risk of death in low-income and middle-income countries than in high-income countries. Substantial reduction of NCD mortality requires policies that considerably reduce tobacco and alcohol use and blood pressure, and equitable access to efficacious and high-quality preventive and curative care for acute and chronic NCDs.
China has made remarkable progress in strengthening its primary health-care system. Nevertheless, the system still faces challenges in structural characteristics, incentives and policies, and quality of care, all of which diminish its preparedness to care for a fifth of the world's population, which is ageing and which has a growing prevalence of chronic non-communicable disease. These challenges include inadequate education and qualifications of its workforce, ageing and turnover of village doctors, fragmented health information technology systems, a paucity of digital data on everyday clinical practice, financial subsidies and incentives that do not encourage cost savings and good performance, insurance policies that hamper the efficiency of care delivery, an insufficient quality measurement and improvement system, and poor performance in the control of risk factors (such as hypertension and diabetes). As China deepens its health-care reform, it has the opportunity to build an integrated, cooperative primary health-care system, generating knowledge from practice that can support improvements, and bolstered by evidence-based performance indicators and incentives.
[1]1Faculty of Sports Science, Ningbo University , Ningbo, China
[2]2Research Academy of Medicine Combining Sports, Ningbo No.2 Hospital , Ningbo, China
[3]3Department of Government and International Studies, Hong Kong Baptist University , Kowloon Tong, Hong Kong SAR, China
[4]4Section of General Internal Medicine, Yale School of Medicine, Yale University , New Haven, CT, United States
[5]5Center for Pain, Research, Informatics, Medical Comorbidities and Education Center
(PRIME), VA Connecticut Healthcare System , West Haven, CT, United States
[6]6Department of Neurology, The First Affiliated Hospital, Sun Yat-Sen University , Guangzhou, China
[7]7Department of Sports, Physical Education and Health, Hong Kong Baptist University , Kowloon Tong, Hong Kong SAR, China
[8]8School of Sports and Health, Nanjing Sport Institute , Nanjing, China
[9]9Centre for Health and Exercise Science Research, Hong Kong Baptist University , Kowloon Tong, Hong Kong SAR, China
Author notes
Edited by: Yanfang Su, University of Washington, United States
Reviewed by: Basil H. Aboul-Enein, University of London, United Kingdom; Chidiebele
Ojukwu, University of Nigeria, Nsukka, Nigeria
This is an open-access article distributed under the terms of the Creative Commons
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is permitted, provided the original author(s) and the copyright owner(s) are credited
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This work was supported by the Research Academy of Medicine Combining Sports, Ningbo
(No.2023001), the Project of NINGBO Leading Medical & Health Discipline (No.2022-F15,
No.2022-F22). GIA was supported by the National Institute of Diabetes, Digestive,
and Kidney Diseases of the National Institutes of Health under a mentored research
scientist development award (K01DK129441).
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