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      Nickel Cobalt Telluride Nanorods for Sensing the Hydrogen Peroxide in Living Cells

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          Abstract

          In this study, we report about the preparation of nickel cobalt telluride nanorods (NiCoTe NRs) by the hydrothermal method using ascorbic acid and cetyltrimethylammonium bromide as reducing agents. The NiCoTe NRs (NCT 1 NRs) were characterized through use of different methods. The nonlinear optical measurements were carried out using Z-scan techniques. The results give the nonlinear absorption that arises from the combined two photon absorption and free carrier absorption. NCT 1 has an excellent electrocatalytic activity toward hydrogen peroxide with a sensitivity of 3464 μA mM –1 cm –2, a wide linear range of 0.002–1835 μM, and the lower detection limit of 0.02 μM, and the prepared electrode was strong in sensing in vivo H 2O 2 free from raw 264.7 cells. Therefore, the binary transition metal chalcogenide based nanostructures have promising potential in live cell biosensing applications.

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          Most cited references23

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          Biosensor based on ultrasmall MoS2 nanoparticles for electrochemical detection of H2O2 released by cells at the nanomolar level.

          Monodispersed surfactant-free MoS2 nanoparticles with sizes of less than 2 nm were prepared from bulk MoS2 by simple ultrasonication and gradient centrifugation. The ultrasmall MoS2 nanoparticles expose a large fraction of edge sites, along with their high surface area, which lead to attractive electrocatalytic activity for reduction of H2O2. An extremely sensitive H2O2 biosensor based on MoS2 nanoparticles with a real determination limit as low as 2.5 nM and wide linear range of 5 orders of magnitude was constructed. On the basis of this biosensor, the trace amount of H2O2 released from Raw 264.7 cells was successfully recorded, and an efficient glucose biosensor was also fabricated. Since H2O2 is a byproduct of many oxidative biological reactions, this work serves as a pathway for the application of MoS2 in the fields of electrochemical sensing and bioanalysis.
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            Graphene quantum dots/gold electrode and its application in living cell H2O2 detection.

            Due to the high peroxidase-like activity and small lateral size of graphene quantum dots (GQDs), the covalently assembled GQDs/Au electrode exhibits great performance and stability in H(2)O(2) detection. It is better or comparable to some enzyme-immobilized electrodes, and thus could be useful in sensing H(2)O(2) changes in biological systems.
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              PtW/MoS 2 hybrid nanocomposite for electrochemical sensing of H 2 O 2 released from living cells

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                Author and article information

                Journal
                ACS Omega
                ACS Omega
                ao
                acsodf
                ACS Omega
                American Chemical Society
                2470-1343
                21 April 2022
                03 May 2022
                : 7
                : 17
                : 14556-14561
                Affiliations
                []Department of Physics, Bharathidasan University , Tiruchirappalli 620 024, India
                []SSN Research Centre, Siva Subramaniya Nadar College of Engineering , Kalavakkam 603110, India
                Author notes
                Author information
                https://orcid.org/0000-0002-9999-6834
                https://orcid.org/0000-0001-6985-0095
                Article
                10.1021/acsomega.1c06007
                9088771
                35557689
                863e077c-5bbb-4612-8558-e6e309fc7e8a
                © 2022 The Authors. Published by American Chemical Society

                Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works ( https://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 05 November 2021
                : 18 March 2022
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                ao1c06007

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