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      Sarcopenia impairs prognosis of patients with liver cirrhosis.

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          Abstract

          Sarcopenia is characterized by the loss of skeletal muscle mass, and is reported to appear in patients with liver cirrhosis (LC). The aim of this study was to investigate the prevalence of sarcopenia in patients with LC, and to test the association between sarcopenia and patient outcomes. We also analyzed the effect of branched-chain amino acid (BCAA) supplementation on sarcopenic LC.

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          Author and article information

          Journal
          Nutrition
          Nutrition (Burbank, Los Angeles County, Calif.)
          1873-1244
          0899-9007
          Jan 2015
          : 31
          : 1
          Affiliations
          [1 ] First Department of Internal Medicine, Gifu University School of Medicine, Yanagido, Gifu, Japan.
          [2 ] First Department of Internal Medicine, Gifu University School of Medicine, Yanagido, Gifu, Japan. Electronic address: Mshiraki-gif@umin.ac.jp.
          [3 ] Center of Nutrition Support and Infection Control, Gifu University Hospital, Yanagido, Gifu, Japan.
          Article
          S0899-9007(14)00344-X
          10.1016/j.nut.2014.07.005
          25441595
          85790f97-8df9-47d8-95e5-32ef04cd2b31
          Copyright © 2015 Elsevier Inc. All rights reserved.
          History

          Branched-chain amino acids,Liver cirrhosis,Protein–energy malnutrition,Sarcopenia,Skeletal muscle index,Survival

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