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      High-speed photoacoustic microscopy: A review dedicated on light sources

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          Abstract

          In recent years, many methods have been investigated to improve imaging speed in photoacoustic microscopy (PAM). These methods mainly focused upon three critical factors contributing to fast PAM: laser pulse repetition rate, scanning speed, and computing power of the microprocessors. A high laser repetition rate is fundamentally the most crucial factor to increase the PAM speed. In this paper, we review methods adopted for fast PAM systems in detail, specifically with respect to light sources. To the best of our knowledge, ours is the first review article analyzing the fundamental requirements for developing high-speed PAM and their limitations from the perspective of light sources.

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          Supercontinuum generation in photonic crystal fiber

          John Dudley, Goëry Genty, Stéphane Coen (2006)
          Article 0 comments Cited 549 times – based on 0 reviews     Review now
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            Photoacoustic tomography: in vivo imaging from organelles to organs.

            Lihong Wang, Song Hu (2012)
            Photoacoustic tomography (PAT) can create multiscale multicontrast images of living biological structures ranging from organelles to organs. This emerging technology overcomes the high degree of scattering of optical photons in biological tissue by making use of the photoacoustic effect. Light absorption by molecules creates a thermally induced pressure jump that launches ultrasonic waves, which are received by acoustic detectors to form images. Different implementations of PAT allow the spatial resolution to be scaled with the desired imaging depth in tissue while a high depth-to-resolution ratio is maintained. As a rule of thumb, the achievable spatial resolution is on the order of 1/200 of the desired imaging depth, which can reach up to 7 centimeters. PAT provides anatomical, functional, metabolic, molecular, and genetic contrasts of vasculature, hemodynamics, oxygen metabolism, biomarkers, and gene expression. We review the state of the art of PAT for both biological and clinical studies and discuss future prospects.
            Article 0 comments Cited 538 times – based on 0 reviews     Review now
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              In vivo photoacoustic tomography of chemicals: high-resolution functional and molecular optical imaging at new depths.

              Chulhong Kim, Christopher Favazza, Lihong Wang (2010)
              Article 0 comments Cited 202 times – based on 0 reviews     Review now
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                Author and article information

                Contributors
                Jeesu Kim
                Sang-Won Lee
                Chang-Seok Kim
                Journal
                Journal ID (nlm-ta): Photoacoustics
                Journal ID (iso-abbrev): Photoacoustics
                Title: Photoacoustics
                Publisher: Elsevier
                ISSN (Electronic): 2213-5979
                Publication date PMC-release: 06 August 2021
                Publication date Collection: December 2021
                Publication date (Electronic): 06 August 2021
                Volume: 24
                Electronic Location Identifier: 100291
                Affiliations
                [a ]Department of Cogno-Mechatronics Engineering, Pusan National University, Busan, 46241, Republic of Korea
                [b ]Department of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, Medical Device Innovation Center, Pohang University of Science and Technology, Pohang, 37673, Republic of Korea
                [c ]Safety Measurement Institute, Korea Research Institute of Standards and Science, Daejeon, 34113, Republic of Korea
                [d ]Department of Bio-Convergence Engineering, Korea University, Seoul, 02841, Republic of Korea
                [e ]Department of Medical Physics, University of Science and Technology, Daejeon, 34113, Republic of Korea
                [f ]Interdisciplinary Program in Precision Public Health, Korea University, Seoul, 02481, Republic of Korea
                Author notes
                [* ]Corresponding authors at: Department of Cogno-Mechatronics Engineering, Pusan National University, Busan, 46241, Republic of Korea. jeesukim@ 123456pusan.ac.kr ckim@ 123456pusan.ac.kr
                [** ]Corresponding author at: Safety Measurement Institute, Korea Research Institute of Standards and Science, Daejeon, 34113, Republic of Korea. swlee76@ 123456kriss.re.kr
                [1]

                These authors contributed equally to this work.

                Article
                Publisher Item ID: S2213-5979(21)00051-3 Publisher ID: 100291
                DOI: 10.1016/j.pacs.2021.100291
                PMC ID: 8403586
                PubMed ID: 34485074
                SO-VID: 84520708-7e23-406e-b17e-4fbbf948917e
                Copyright © © 2021 The Author(s)
                License:

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                Date received : 28 April 2021
                Date revision received : 18 July 2021
                Date accepted : 3 August 2021
                Categories
                Subject: Research Article

                Keywords: photoacoustic microscopy,high-speed imaging,light sources,fiber laser
                Data availability:
                Keywords: photoacoustic microscopy, high-speed imaging, light sources, fiber laser

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