Te-Sheng Chang: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: ResourcesRole: Writing – original draft
Ying-Huang Tsai: Role: ConceptualizationRole: Writing – original draft
Yi-Heng Lin: Role: Data curationRole: Formal analysis
Chun-Hsien Chen: Role: Data curationRole: Formal analysisRole: InvestigationRole: Resources
Chung-Kuang Lu: Role: Data curationRole: Formal analysisRole: InvestigationRole: Resources
Wen-Shih Huang: Role: ConceptualizationRole: Writing – review & editing
Yao-Hsu Yang: Role: Data curationRole: Formal analysisRole: InvestigationRole: Resources
Wei-Ming Chen: Role: ConceptualizationRole: Writing – review & editing
Yung-Yu Hsieh: Role: ConceptualizationRole: Writing – review & editing
Yu-Chih Wu: Role: ConceptualizationRole: Writing – review & editing
Shui-Yi Tung: Role: ConceptualizationRole: MethodologyRole: SupervisionRole: Writing – original
draftRole: Writing – review & editing
Yen-Hua Huang:
ORCID: http://orcid.org/0000-0001-6020-9998
Role: ConceptualizationRole: MethodologyRole: SupervisionRole: Writing – original
draftRole: Writing – review & editing
Yap Boum II: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
21
February
2020
Publication date Collection: 2020
Volume: 15
Issue: 2
Electronic Location Identifier: e0229101
Affiliations
[1
]
Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Chiayi,
Taiwan
[2
]
College of Medicine, Chang Gung University, Taoyuan, Taiwan
[3
]
Department of Biochemistry and Molecular Cell Biology, College of Medicine, Taipei
Medical University, Taipei, Taiwan
[4
]
Department of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital,
Chiayi, Taiwan
[5
]
Research Center for Cell Therapy and Regeneration Medicine, Taipei Medical University,
Taipei, Taiwan
[6
]
Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital,
Chiayi, Taiwan
[7
]
Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi,
Taiwan
[8
]
Health Information and Epidemiology Laboratory of Chang Gung Memorial Hospital, Chiayi,
Taiwan
[9
]
Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University,
Taipei, Taiwan
[10
]
Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei, Taiwan
[11
]
Comprehensive Cancer Center of Taipei Medical University, Taipei, Taiwan
[12
]
International PhD Program for Cell Therapy and Regeneration Medicine, College of Medicine,
Taipei Medical University, Taipei, Taiwan
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-19-23985
DOI: 10.1371/journal.pone.0229101
PMC ID: 7034903
PubMed ID: 32084186
SO-VID: 83146e55-db4b-4d28-9923-ee99cbc40476
Copyright © © 2020 Chang et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100012553, Chang Gung Memorial Hospital;
Award ID: CORPG6F0053
Award Recipient
:
Te-Sheng Chang
This work was supported by research grants from Chang Gung Memorial Hospital, Taiwan
(CORPG6F0053) to TSC, and the Ministry of Science and Technology, Taiwan (MOST 106-2314-B-182-065
to TSC; MOST108-2314-B-038-006 and MOST108-2321-B-038-003 to YHH). The funders had
no role in study design, data collection and analysis, decision to publish, or preparation
of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Signs and Symptoms
Subject:
Hemorrhage
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Signs and Symptoms
Subject:
Hemorrhage
Subject:
Medicine and Health Sciences
Subject:
Vascular Medicine
Subject:
Hemorrhage
Subject:
Medicine and Health Sciences
Subject:
Public and Occupational Health
Subject:
Preventive Medicine
Subject:
Prophylaxis
Subject:
Antibiotic Prophylaxis
Subject:
Medicine and Health Sciences
Subject:
Gastroenterology and Hepatology
Subject:
Liver Diseases
Subject:
Cirrhosis
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Drugs
Subject:
Antimicrobials
Subject:
Antibiotics
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Microbial Control
Subject:
Antimicrobials
Subject:
Antibiotics
Subject:
Medicine and Health Sciences
Subject:
Infectious Diseases
Subject:
Bacterial Diseases
Subject:
Biology and life sciences
Subject:
Microbiology
Subject:
Medical microbiology
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Hepatitis viruses
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Hepatitis B virus
Subject:
Medicine and health sciences
Subject:
Pathology and laboratory medicine
Subject:
Pathogens
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Hepatitis viruses
Subject:
Hepatitis B virus
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral pathogens
Subject:
Hepatitis viruses
Subject:
Hepatitis B virus
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
RNA viruses
Subject:
Flaviviruses
Subject:
Hepacivirus
Subject:
Hepatitis C virus
Subject:
Biology and life sciences
Subject:
Microbiology
Subject:
Medical microbiology
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Flaviviruses
Subject:
Hepacivirus
Subject:
Hepatitis C virus
Subject:
Medicine and health sciences
Subject:
Pathology and laboratory medicine
Subject:
Pathogens
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Flaviviruses
Subject:
Hepacivirus
Subject:
Hepatitis C virus
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral pathogens
Subject:
Flaviviruses
Subject:
Hepacivirus
Subject:
Hepatitis C virus
Subject:
Biology and life sciences
Subject:
Microbiology
Subject:
Medical microbiology
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Hepatitis viruses
Subject:
Hepatitis C virus
Subject:
Medicine and health sciences
Subject:
Pathology and laboratory medicine
Subject:
Pathogens
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Hepatitis viruses
Subject:
Hepatitis C virus
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral pathogens
Subject:
Hepatitis viruses
Subject:
Hepatitis C virus
Subject:
Medicine and Health Sciences
Subject:
Surgical and Invasive Medical Procedures
Subject:
Endoscopy