Characterization of RNA-Binding Motif 3 (RBM3) Protein Levels and Nuclear Architecture Changes in Aggressive and Recurrent Prostate Cancer.

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Abstract

The RNA-binding motif protein 3 (RBM3) has been shown to be up-regulated in several types of cancer, including prostate cancer (PCa), compared to normal tissues. Increased RBM3 nuclear expression has been linked to improved clinical outcomes.

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Journal

Journal ID (iso-abbrev): Cancer Rep (Hoboken)

Title: Cancer reports (Hoboken, N.J.)

Publisher: Wiley

ISSN (Electronic): 2573-8348

ISSN (Print): 2573-8348

Publication date (Electronic): June 2020

Volume: 3

Issue: 3

Affiliations

[1 ] The James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

[2 ] Statistical Consultant, Quakertown, Pennsylvania.

[3 ] Department of Medical Oncology and Therapeutics Research, City of Hope, Duarte, California.

Article

Mid ID: NIHMS1065884

DOI: 10.1002/cnr2.1237

PMC ID: 7316183

PubMed ID: 32587951

SO-VID: 81841f8b-4e1c-4b0e-af76-a8845ce7bef2

History

Keywords: nuclear morphometry,biochemical recurrence,RBM3,tumor aggressiveness,prostate cancer

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Keywords: nuclear morphometry, biochemical recurrence, RBM3, tumor aggressiveness, prostate cancer

Characterization of RNA-Binding Motif 3 (RBM3) Protein Levels and Nuclear Architecture Changes in Aggressive and Recurrent Prostate Cancer.

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Abstract

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Higher order chromatin architecture

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