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Induction of labour at term with oral misoprostol versus a Foley catheter (PROBAAT-II): a multicentre randomised controlled non-inferiority trial
Mieke L G ten Eikelder ,
Katrien Oude Rengerink ,
Marta Jozwiak ,
Jan W de Leeuw ,
Irene M de Graaf ,
Mariëlle G van Pampus ,
Marloes Holswilder ,
Martijn A Oudijk ,
Gert-Jan van Baaren ,
Paula J M Pernet ,
Caroline Bax ,
Gijs A van Unnik ,
Gratia Martens ,
Martina Porath ,
Huib van Vliet ,
Robbert J P Rijnders ,
A Hanneke Feitsma ,
Frans J M E Roumen ,
Aren J van Loon ,
Hans Versendaal ,
Martin J N Weinans ,
Mallory Woiski ,
Erik van Beek ,
Brenda Hermsen ,
Ben Willem Mol ,
Kitty W M Bloemenkamp
April 2016
April 2016
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Abstract
Labour is induced in 20-30% of all pregnancies. In women with an unfavourable cervix,
both oral misoprostol and Foley catheter are equally effective compared with dinoprostone
in establishing vaginal birth, but each has a better safety profile. We did a trial
to directly compare oral misoprostol with Foley catheter alone.
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Most cited references19
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ACOG Practice Bulletin No. 107: Induction of labor.
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Immediate delivery versus expectant monitoring for hypertensive disorders of pregnancy between 34 and 37 weeks of gestation (HYPITAT-II): an open-label, randomised controlled trial
Jan M J Sporken, Josje Langenveld, Maureen Franssen … (2015)
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Vaginal misoprostol for cervical ripening and induction of labour.
G Hofmeyr, A Gülmezoglu, Cynthia Pileggi (2010)