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      Intraoperative CT-guided navigation versus fluoroscopy for percutaneous pedicle screw placement in 192 patients: a comparative analysis

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          Abstract

          Background

          Percutaneous pedicle screw (PPS) placement is a key step in several minimally invasive spinal surgery (MISS) procedures. Traditional technique for PPS makes use of C-arm fluoroscopy assistance (FA). More recently, newer intraoperative imaging techniques have been developed for PPS, including CT-guided navigation (CTNav). The aim of this study was to compare FA and CTNav techniques for PPS with regard to accuracy, complications, and radiation dosage.

          Materials and methods

          A total of 192 patients with degenerative lumbar spondylolisthesis and canal stenosis who underwent MISS posterior fusion ± interbody fusion through transforaminal approach (TLIF) were retrospectively reviewed. Pedicle screws were placed percutaneously using either standard C-arm fluoroscopy guidance (FA group) or CT navigation (CTNav group). Intraoperative effective dose (ED, mSv) was measured. Screw placement accuracy was assessed postoperatively on a CT scan using Gertzbein and Robbins classification (grades A–E). Oswestry disability index (ODI) and visual analog scale (VAS) scores were compared in both groups before and after surgery.

          Results

          A total of 101 and 91 procedures were performed with FA (FA group) and CTNav approach (CTNav group), respectively. Median age was 61 years in both groups, and the most commonly treated level was L4–L5. Median ED received from patients was 1.504 mSv (0.494–4.406) in FA technique and 21.130 mSv (10.840–30.390) in CTNav approach ( p < 0.001). Percentage of grade A and B screws was significantly higher for the CTNav group (96.4% versus 92%, p < 0.001), whereas there were 16 grade E screws in the FA group and 0 grade E screws in the CTNav group ( p < 0.001). A total of seven and five complications were reported in the FA and CTNav group, respectively ( p = 0.771).

          Conclusions

          CTNav technique increases accuracy of pedicle screw placement compared with FA technique without affecting operative time. Nevertheless, no significant difference was noted in terms of reoperation rate due to screw malpositioning between CTNav and FA techniques. Radiation exposure of patients was significantly higher with CTNav technique.

          Level of Evidence: Level 3.

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          Most cited references29

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          Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer.

          Use of computed tomography (CT) for diagnostic evaluation has increased dramatically over the past 2 decades. Even though CT is associated with substantially higher radiation exposure than conventional radiography, typical doses are not known. We sought to estimate the radiation dose associated with common CT studies in clinical practice and quantify the potential cancer risk associated with these examinations. We conducted a retrospective cross-sectional study describing radiation dose associated with the 11 most common types of diagnostic CT studies performed on 1119 consecutive adult patients at 4 San Francisco Bay Area institutions in California between January 1 and May 30, 2008. We estimated lifetime attributable risks of cancer by study type from these measured doses. Radiation doses varied significantly between the different types of CT studies. The overall median effective doses ranged from 2 millisieverts (mSv) for a routine head CT scan to 31 mSv for a multiphase abdomen and pelvis CT scan. Within each type of CT study, effective dose varied significantly within and across institutions, with a mean 13-fold variation between the highest and lowest dose for each study type. The estimated number of CT scans that will lead to the development of a cancer varied widely depending on the specific type of CT examination and the patient's age and sex. An estimated 1 in 270 women who underwent CT coronary angiography at age 40 years will develop cancer from that CT scan (1 in 600 men), compared with an estimated 1 in 8100 women who had a routine head CT scan at the same age (1 in 11 080 men). For 20-year-old patients, the risks were approximately doubled, and for 60-year-old patients, they were approximately 50% lower. Radiation doses from commonly performed diagnostic CT examinations are higher and more variable than generally quoted, highlighting the need for greater standardization across institutions.
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            Accuracy of pedicle screw placement: a systematic review of prospective in vivo studies comparing free hand, fluoroscopy guidance and navigation techniques.

            With the advances and improvement of computer-assisted surgery devices, computer-guided pedicle screws insertion has been applied to the lumbar, thoracic and cervical spine. The purpose of the present study was to perform a systematic review of all available prospective evidence regarding pedicle screw insertion techniques in the thoracic and lumbar human spine. We considered all prospective in vivo clinical studies in the English literature that assessed the results of different pedicle screw placement techniques (free-hand technique, fluoroscopy guided, computed tomography (CT)-based navigation, fluoro-based navigation). MEDLINE, OVID, and Springer databases were used for the literature search covering the period from January 1950 until May 2010. 26 prospective clinical studies were eventually included in the analysis. These studies included in total 1,105 patients in which 6,617 screws were inserted. In the studies using free-hand technique, the percentage of the screws fully contained in the pedicle ranged from 69 to 94%, with the aid of fluoroscopy from 28 to 85%, using CT navigation from 89 to 100% and using fluoroscopy-based navigation from 81 to 92%. The screws positioned with free-hand technique tended to perforate the cortex medially, whereas the screws placed with CT navigation guidance seemed to perforate more often laterally. In conclusion, navigation does indeed exhibit higher accuracy and increased safety in pedicle screw placement than free-hand technique and use of fluoroscopy.
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              Accuracy of Pedicular Screw Placement In Vivo

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                Author and article information

                Contributors
                giularocca86@gmail.com
                edoardo.mazzucchi@gmail.com , edoardo.mazzucchi@materolbia.com
                fabrizio.pignotti@materolbia.com
                luigianasto@gmail.com
                gianluca.galieri@gmail.com
                alessandro.olivi@policlinicogemelli.it
                vincenzo.desantis@policlinicogemelli.it
                pierluigi.rinaldi@materolbia.it
                enricopola@hotmail.com
                giovanni.sabatino@policlinicogemelli.it
                Journal
                J Orthop Traumatol
                J Orthop Traumatol
                Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology
                Springer International Publishing (Cham )
                1590-9921
                1590-9999
                1 September 2022
                1 September 2022
                December 2022
                : 23
                : 44
                Affiliations
                [1 ]GRID grid.513825.8, ISNI 0000 0004 8503 7434, Department of Neurosurgery, , Mater Olbia Hospital, ; Olbia, Italy
                [2 ]GRID grid.8142.f, ISNI 0000 0001 0941 3192, Institute of Neurosurgery, , IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Catholic University, ; Rome, Italy
                [3 ]GRID grid.513825.8, ISNI 0000 0004 8503 7434, Neurosurgical Training Center and Brain Research, , Mater Olbia Hospital, ; Olbia, Italy
                [4 ]GRID grid.8142.f, ISNI 0000 0001 0941 3192, Institute of Orthopedics, , IRCCS Fondazione Policlinico Universitario Agostino Gemelli, Catholic University of Rome, ; Rome, Italy
                [5 ]GRID grid.513825.8, ISNI 0000 0004 8503 7434, Unit of Orthopedics, , Mater Olbia Hospital, ; Olbia, Italy
                [6 ]GRID grid.513825.8, ISNI 0000 0004 8503 7434, Unit of Radiology, , Mater Olbia Hospital, ; Olbia, Italy
                [7 ]GRID grid.411293.c, ISNI 0000 0004 1754 9702, Unit of Orthopedics and Spine Surgery, , Primo Policlinico Di Napoli, Università Della Campania Luigi Vanvitelli, ; Piazza Luigi Miraglia, 2, 80138 Naples, Italy
                Article
                661
                10.1186/s10195-022-00661-8
                9437178
                36048284
                8047bedf-3659-4763-abcd-c0ae50bfa447
                © The Author(s) 2022

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 10 November 2021
                : 3 August 2022
                Categories
                Original Article
                Custom metadata
                © The Author(s) 2022

                Orthopedics
                minimally invasive spine surgery,percutaneous pedicle screws,ct navigation,degenerative spondylolisthesis,low-back-pain surgery,radiation exposure

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