Complete eradication of hepatocellular carcinomas by combined vasostatin gene therapy and B7H3-mediated immunotherapy.

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Abstract

B7H3 immunogene therapy is able to completely eradicate tumors when combined with an anti-vascular agent. The aim of this study was to determine whether vasostatin, a potent anti-angiogenic agent, could synergize with B7H3-mediated immunotherapy to combat hepatocellular carcinoma (HCC).

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Journal

Journal ID (iso-abbrev): J. Hepatol.

Title: Journal of hepatology

Publisher: Elsevier BV

ISSN: 0168-8278

ISSN (Print): 0168-8278

Publication date (Electronic): Jan 2007

Volume: 46

Issue: 1

Affiliations

[1 ] The Hepatosplenic Surgery Center of Heilongjiang Province/Department of General Surgery, The First Clinical College of Harbin Medical University, Harbin 150001, China.

Article

Publisher Item ID: S0168-8278(06)00462-4

DOI: 10.1016/j.jhep.2006.07.031

PubMed ID: 17109987

SO-VID: 7ee5e5a7-f90e-4339-b885-f543f6404c9f

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