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      Intelligent Telehealth in Pharmacovigilance: A Future Perspective

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          Abstract

          Pharmacovigilance improves patient safety by detecting and preventing adverse drug events. However, challenges exist that limit adverse drug event detection, resulting in many adverse drug events being underreported or inaccurately reported. One challenge includes having access to large data sets from various sources including electronic health records and wearable medical devices. Artificial intelligence, including machine learning methods, such as natural language processing and deep learning, can detect and extract information about adverse drug events, thus automating the pharmacovigilance process and improving the surveillance of known and documented adverse drug events. In addition, with the increased demand for telehealth services, for managing both acute and chronic diseases, artificial intelligence methods can play a role in detecting and preventing adverse drug events. In this review, we discuss two use cases of how artificial intelligence methods may be useful to improve the quality of pharmacovigilance and the role of artificial intelligence in telehealth practices.

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          Deep learning.

          Deep learning allows computational models that are composed of multiple processing layers to learn representations of data with multiple levels of abstraction. These methods have dramatically improved the state-of-the-art in speech recognition, visual object recognition, object detection and many other domains such as drug discovery and genomics. Deep learning discovers intricate structure in large data sets by using the backpropagation algorithm to indicate how a machine should change its internal parameters that are used to compute the representation in each layer from the representation in the previous layer. Deep convolutional nets have brought about breakthroughs in processing images, video, speech and audio, whereas recurrent nets have shone light on sequential data such as text and speech.
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            Is Open Access

            Artificial intelligence in healthcare: past, present and future

            Artificial intelligence (AI) aims to mimic human cognitive functions. It is bringing a paradigm shift to healthcare, powered by increasing availability of healthcare data and rapid progress of analytics techniques. We survey the current status of AI applications in healthcare and discuss its future. AI can be applied to various types of healthcare data (structured and unstructured). Popular AI techniques include machine learning methods for structured data, such as the classical support vector machine and neural network, and the modern deep learning, as well as natural language processing for unstructured data. Major disease areas that use AI tools include cancer, neurology and cardiology. We then review in more details the AI applications in stroke, in the three major areas of early detection and diagnosis, treatment, as well as outcome prediction and prognosis evaluation. We conclude with discussion about pioneer AI systems, such as IBM Watson, and hurdles for real-life deployment of AI.
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              Artificial intelligence in healthcare

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                Author and article information

                Contributors
                dbates@bwh.harvard.edu
                Journal
                Drug Saf
                Drug Saf
                Drug Safety
                Springer International Publishing (Cham )
                0114-5916
                1179-1942
                17 May 2022
                2022
                : 45
                : 5
                : 449-458
                Affiliations
                [1 ]GRID grid.62560.37, ISNI 0000 0004 0378 8294, Division of General Internal Medicine, , Brigham and Women’s Hospital, ; Boston, MA USA
                [2 ]GRID grid.416498.6, ISNI 0000 0001 0021 3995, Department of Pharmacy Practice, , MCPHS University, ; Boston, MA USA
                [3 ]GRID grid.38142.3c, ISNI 000000041936754X, Harvard Medical School, ; 1620 Tremont St., 3rd Floor, Boston, MA 02120 USA
                [4 ]GRID grid.38142.3c, ISNI 000000041936754X, Department of Health Policy and Management, , Harvard School of Public Health, ; Boston, MA USA
                Author information
                http://orcid.org/0000-0001-6268-1540
                Article
                1172
                10.1007/s40264-022-01172-5
                9112241
                35579810
                7e989f58-b7d3-4f60-81d2-76d1770b4dd3
                © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 2 March 2022
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                © Springer Nature Switzerland AG 2022

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