Evaluation of Anti-inflammatory and Anti-arthritic activity of Luffa acutangula peel extract mediated ZnO nanoparticles

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

The special improved characteristics and different application of zinc oxide nanoparticles made them to play a major role among metal oxide nanoparticles. Zinc oxide nanoparticles were successfully synthesized in a cost effective, time saving and safety method using Luffa acutangula peel extract. Zinc oxide nanoparticles showed maximum absorption peak at 377.77nm in UV visible absorption spectroscopic studies. The fourier transform infrared spectroscopy (FTIR) studies revealed the presence of various functional groups attributed by aqueous peel extract along with the zinc oxide nanoparticles. The shape of the zinc oxide nanoparticles was found to be spherical under scanning electron microscopy and they were found to be agglomerated. The zinc oxide nanoparticles prepared using Luffa acutangula showed anti-inflammatory activity when studied by Human RBC membrane stabilization method. Also they effectively inhibited the egg albumin and bovine serum albumin denaturation by which they are confirmed to have anti-arthritic activity.

Related collections

Most cited references 18

Record: found
Abstract: found
Article: not found

A review on biogenic synthesis of ZnO nanoparticles using plant extracts and microbes: A prospect towards green chemistry.

Shakeel Ahmed, Annu, Saif Chaudhry … (2017)

Nanotechnology is emerging as an important area of research with its tremendous applications in all fields of science, engineering, medicine, pharmacy, etc. It involves the materials and their applications having one dimension in the range of 1-100nm. Generally, various techniques are used for syntheses of nanoparticles (NPs) viz. laser ablation, chemical reduction, milling, sputtering, etc. These conventional techniques e.g. chemical reduction method, in which various hazardous chemicals are used for the synthesis of NPs later become liable for innumerable health risks due to their toxicity and endangering serious concerns for environment, while other approaches are expensive, need high energy for the synthesis of NPs. However, biogenic synthesis method to produce NPs is eco-friendly and free of chemical contaminants for biological applications where purity is of concerns. In biological method, different biological entities such as extract, enzymes or proteins of a natural product are used to reduce and stabilised formation of NPs. The nature of these biological entities also influence the structure, shape, size and morphology of synthesized NPs. In this review, biogenic synthesis of zinc oxide (ZnO) NPs, procedures of syntheses, mechanism of formation and their various applications have been discussed. Various entities such as proteins, enzymes, phytochemicals, etc. available in the natural reductants are responsible for synthesis of ZnO NPs.