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      Orosensory detection of bitter in fat-taster healthy and obese participants: Genetic polymorphism of CD36 and TAS2R38.

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          Abstract

          We assessed orosensory detection of a long-chain fatty acid, linoleic acid (LA), and a bitter taste marker, 6-n-propylthiouracil (PROP), and correlated lipid-taster subjects with PROP detection and polymorphism in genes encoding bitter and lipid taste receptors, respectively, TAS2R38 and CD36, in normal weight and obese subjects.

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          Author and article information

          Journal
          Clin Nutr
          Clinical nutrition (Edinburgh, Scotland)
          Elsevier BV
          1532-1983
          0261-5614
          Jun 21 2017
          Affiliations
          [1 ] Higher School of Health and Technical Sciences, Tunis El Manar University, Tunisia; Physiologie de la Nutrition & Toxicologie, INSERM UMR 1231, Université de Bourgogne-Franche Comté (UBFC), Dijon, France; Faculté des Sciences de Bizerte, Jarzouna-Bizerte, Tunisia.
          [2 ] Physiologie de la Nutrition & Toxicologie, INSERM UMR 1231, Université de Bourgogne-Franche Comté (UBFC), Dijon, France; Laboratory of Neurobiology and Molecular Psychiatry, Laboratory of Molecular Physiology, Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.
          [3 ] Physiologie de la Nutrition & Toxicologie, INSERM UMR 1231, Université de Bourgogne-Franche Comté (UBFC), Dijon, France; Département de Biochimie, Biologie Cellulaire et Moléculaire, Université des Frères Mentouri, Constantine 1, Alegria.
          [4 ] Laboratory of Neurobiology and Molecular Psychiatry, Laboratory of Molecular Physiology, Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic; Institute of Animal Physiology and Genetics, Academy of Science, Brno, Czech Republic.
          [5 ] Institut National de Nutrition et de Technologie Alimentaire de Tunis, Djebel Lakhdar, Bab Saadoun, Tunis, Tunisia.
          [6 ] Higher School of Health and Technical Sciences, Tunis El Manar University, Tunisia.
          [7 ] Physiologie de la Nutrition & Toxicologie, INSERM UMR 1231, Université de Bourgogne-Franche Comté (UBFC), Dijon, France. Electronic address: Naim.Khan@u-bourgogne.fr.
          Article
          S0261-5614(17)30215-7
          10.1016/j.clnu.2017.06.004
          28669668
          7d02df76-351e-487a-81c5-9d65f0efd589
          History

          Bitter taste,Fat taste,Genetic polymorphism,Obesity
          Bitter taste, Fat taste, Genetic polymorphism, Obesity

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