Randomized controlled trial of cognitive behavioural therapy for depressive and anxiety symptoms in Chinese women with breast cancer.

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Abstract

Depressive and anxiety symptoms are frequently observed in breast cancer survivors. To date, few randomized controlled trials have been conducted on the efficacy of cognitive behavioural therapy (CBT) for depressive and anxiety symptoms in Chinese population. This study aims to verify the efficacy of CBT in Chinese breast cancer survivors. Women (n = 392) with breast cancer were randomly assigned to 3 groups: CBT (n = 98), self-care management (SCM, n = 98), and usual care (UC, n = 196) using the proportion 1:1:2. Women in the CBT and SCM groups received a series of nine sessions for 12 weeks, while women in the UC group received their usual medical care only. Depressive and anxiety symptoms were assessed using the Hamilton Depression Rating Scale (HAMD) and the Hamilton Anxiety Scale (HAMA) score at baseline, 2, 4, 8, 12, 16, and 24 weeks. A significant intergroup difference was found in the HAMD and HAMA scores. Women in the CBT group showed significantly less depressive and anxiety symptoms compared with women in the SCM and UC groups over time. In conclusion, this study supports the efficacy of CBT for depressive and anxiety symptoms in Chinese breast cancer survivors.

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Author and article information

Journal

Journal ID (iso-abbrev): Psychiatry Res

Title: Psychiatry research

Publisher: Elsevier BV

ISSN (Electronic): 1872-7123

ISSN (Print): 0165-1781

Publication date (Electronic): January 2019

Volume: 271

Affiliations

[1 ] Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.

[2 ] Department of Medical Psychology, Public Health Institute of Harbin Medical University, Harbin 150081, China.

[3 ] Medical Psychological Institute, Second Xiangya Hospital, Central South University, Changsha 410012, China.

[4 ] Department of Psychiatry, the First Affiliated Hospital of Anhui Medical University, Hefei 230601, China.

[5 ] Department of Preventive Medicine, Wenzhou Medical University, Wenzhou 325000, China.

[6 ] Department of Neurology, Renmin Hospital of Wuhan University, Wuhan 430000, China.

[7 ] Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.

[8 ] Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.

[9 ] Department of Psychology, Wenzhou Medical University, Wenzhou 325000, China.

[10 ] Department of Psychiatry, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China.

[11 ] Department of Psychiatry, Dujiangyan Third People's Hospital, Sichuan 611800, China.

[12 ] Yinzhou Hospital Affiliated To Medical School of Ningbo University, Ningbo 315175, China.

[13 ] Department of Oncology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.

[14 ] Key Laboratory of Laboratory Medicine, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou 325000, China. Electronic address: xguo1@cdc.gov.

[15 ] Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China; Department of Psychology, Wenzhou Medical University, Wenzhou 325000, China. Electronic address: hjc@wmu.edu.cn.

Article

Publisher Item ID: S0165-1781(18)30496-7

DOI: 10.1016/j.psychres.2018.11.026

PubMed ID: 30469089

SO-VID: 7ced6a45-4e43-4daf-a52f-e8c15c31239c

History

Keywords: Chinese population,Follow-up,Psychological symptom,Psychotherapy

Data availability:

Keywords: Chinese population, Follow-up, Psychological symptom, Psychotherapy

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