The influence of age and gender on motor and non-motor features of early Parkinson&apos;s disease: initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Identifying factors influencing phenotypic heterogeneity in Parkinson's Disease is crucial for understanding variability in disease severity and progression. Age and gender are two most basic epidemiological characteristics, yet their effect on expression of PD symptoms is not fully defined. We aimed to delineate effects of age and gender on the phenotype in an incident cohort of PD patients and healthy controls from the Oxford Parkinson Disease Centre (OPDC).

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Parkinsonism Relat Disord

Title: Parkinsonism & related disorders

Publisher: Elsevier BV

ISSN (Electronic): 1873-5126

ISSN (Print): 1353-8020

Publication date (Electronic): Jan 2014

Volume: 20

Issue: 1

Affiliations

[1 ] Nuffield Department of Clinical Neurosciences, Division of Clinical Neurology, University of Oxford, Oxford, United Kingdom; Oxford Parkinson Disease Centre, University of Oxford, Oxford, United Kingdom.

[2 ] Northampton General Hospital, Northampton, United Kingdom.

[3 ] Oxford Parkinson Disease Centre, University of Oxford, Oxford, United Kingdom; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.

[4 ] Nuffield Department of Clinical Neurosciences, Division of Clinical Neurology, University of Oxford, Oxford, United Kingdom; Oxford Parkinson Disease Centre, University of Oxford, Oxford, United Kingdom; Department of Clinical Neurology, John Radcliffe Hospital, Oxford, United Kingdom.

[5 ] Oxford Parkinson Disease Centre, University of Oxford, Oxford, United Kingdom; School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

[6 ] Nuffield Department of Clinical Neurosciences, Division of Clinical Neurology, University of Oxford, Oxford, United Kingdom; Oxford Parkinson Disease Centre, University of Oxford, Oxford, United Kingdom; Department of Clinical Neurology, John Radcliffe Hospital, Oxford, United Kingdom. Electronic address: michele.hu@ndcn.ox.ac.uk.

Article

Publisher Item ID: S1353-8020(13)00356-8

DOI: 10.1016/j.parkreldis.2013.09.025

PubMed ID: 24183678

SO-VID: 7cd568c7-e011-495d-ae14-2453c58c80a7

History

Keywords: Cohort study,Epidemiology,Parkinson's disease

Data availability:

Keywords: Cohort study, Epidemiology, Parkinson's disease

Comments

Comment on this article

scite_

Cited by 114

See all cited by

- Version 1

The influence of age and gender on motor and non-motor features of early Parkinson's disease: initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort.

Read this article at