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      How Efficacious Are Patient Education Interventions to Improve Bowel Preparation for Colonoscopy? A Systematic Review

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          Abstract

          Background

          Bowel preparation is inadequate in a large proportion of colonoscopies, leading to multiple clinical and economic harms. While most patients receive some form of education before colonoscopy, there is no consensus on the best approach.

          Aims

          This systematic review aimed to evaluate the efficacy of patient education interventions to improve bowel preparation.

          Methods

          We searched the Cochrane Database, CINAHL, EMBASE, Ovid, and Web of Science. Inclusion criteria were: (1) a patient education intervention; (2) a primary aim of improving bowel preparation; (3) a validated bowel preparation scale; (4) a prospective design; (5) a concurrent control group; and, (6) adult participants. Study validity was assessed using a modified Downs and Black scale.

          Results

          1,080 abstracts were screened. Seven full text studies met inclusion criteria, including 2,660 patients. These studies evaluated multiple delivery platforms, including paper-based interventions (three studies), videos (two studies), re-education telephone calls the day before colonoscopy (one study), and in-person education by physicians (one study). Bowel preparation significantly improved with the intervention in all but one study. All but one study were done in a single center. Validity scores ranged from 13 to 24 (maximum 27). Four of five abstracts and research letters that met inclusion criteria also showed improvements in bowel preparation. Statistical and clinical heterogeneity precluded meta-analysis.

          Conclusion

          Compared to usual care, patient education interventions appear efficacious in improving the quality of bowel preparation. However, because of the small scale of the studies and individualized nature of the interventions, results of these studies may not be generalizable to other settings. Healthcare practices should consider systematically evaluating their current bowel preparation education methods before undertaking new interventions.

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          Most cited references28

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          Quality indicators for colonoscopy.

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            Validation of a new scale for the assessment of bowel preparation quality.

            Bowel preparation quality scales are used to document the superiority of one preparation regime vs. another. The validity and reliability of these scales are not routinely stated in reports of studies in which the scales are used. A new colonoscopy bowel preparation scale (the Ottawa bowel preparation scale) was developed and validated prospectively. Ninety-seven consecutive patients undergoing elective outpatient colonoscopy were entered into the study. The quality of the bowel preparation was assessed independently by two investigators who used the Ottawa scale, and the only other validated scale (Aronchick scale) that could be identified. The interobserver agreement and reliability of each scale was assessed by the Pearson correlation coefficient (r), the intraclass correlation coefficient, and regression analysis. The Pearson correlation coefficients were, respectively, 0.89 and 0.62 for the Ottawa and Aronchick scales (p<0.001). The values for the kappa statistic, an intraclass correlation coefficient measuring agreement over and above chance agreement, were, respectively, 0.94 and 0.77 (p<0.001). Linear regression analysis, mapping the line best describing the scatter of scores by raters, for the Ottawa scale revealed a slope of the line of 0.93 and a y intercept of 0.10. The Aronchick scale revealed a slope of 0.65 and a y intercept of 0.46. The Ottawa scale thus was closer to an identity line comparing raters (i.e., closer to a line with slope of 1.00 and y intercept of 0.00). The Ottawa scale demonstrated a right colon kappa (intraclass correlation coefficient) of 0.92: 95% CI[0.88, 0.95], a mid colon kappa (intraclass correlation coefficient) of 0.88: 95% CI[0.82, 0.92], and a rectosigmoid kappa (intraclass correlation coefficient) of 0.89: 95% CI[0.83, 0.92]. The Ottawa scale was validated prospectively and demonstrates high interobserver agreement and reliability, whether used as a total score or for individual colon segments.
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              Validated Scales for Colon Cleansing: A Systematic Review.

              Bowel cleanliness is a critical determinant of colonoscopy quality, mandating its standardized assessment, yet bowel preparation scales have been variably validated. The objective of this study was to assess validity and reliability of existing bowel preparation scales.
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                Author and article information

                Contributors
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                14 October 2016
                2016
                : 11
                : 10
                : e0164442
                Affiliations
                [1 ]Department of Internal Medicine, University of Michigan Medical School, 1500 E. Medical Center Dr, Ann Arbor, MI, United States of America
                [2 ]Veterans Affairs Ann Arbor Health Care System, 2215 Fuller Rd, Ann Arbor, MI, 48105, United States of America
                [3 ]Veterans Affairs Center for Clinical Management Research, 2215 Fuller Rd, Ann Arbor, 48105, MI, United States of America
                [4 ]Department of Health Behavior and Health Education, University of Michigan School of Public Health, 3790 SPH I, 1415 Washington Heights, Ann Arbor, MI, 48109, United States of America
                University Hospital Llandough, UNITED KINGDOM
                Author notes

                Competing Interests: Dr. Kurlander has received unrestricted research funding from Ironwood Pharmaceuticals ( https://www.ironwoodpharma.com/), and Dr. Schoenfeld serves as a consultant for Salix Pharmaceuticals ( https://www.salix.com/). These do not alter our adherence to PLOS ONE policies on sharing data and materials.

                • Conceptualization: JEK ARS AKW SBM CMC PSS SDS.

                • Investigation: JEK ARS SDS.

                • Methodology: JEK ARS AKW SBM CMC PSS SDS.

                • Writing – original draft: JEK ARS SDS.

                • Writing – review & editing: JEK ARS AKW SBM CMC PSS SDS.

                ‡ These authors are co-primary authors on this work.

                Article
                PONE-D-16-20769
                10.1371/journal.pone.0164442
                5065159
                27741260
                7cc01485-1f3e-43be-a54e-a835dbd9b5cd

                This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

                History
                : 23 May 2016
                : 26 September 2016
                Page count
                Figures: 1, Tables: 3, Pages: 14
                Funding
                Dr. Waljee’s research is funded by a VA HSR&D CDA-2 Career Development Award 1IK2HX000775.
                Categories
                Research Article
                Medicine and Health Sciences
                Health Care
                Patients
                Medicine and Health Sciences
                Surgical and Invasive Medical Procedures
                Digestive System Procedures
                Colonoscopy
                Research and Analysis Methods
                Database and Informatics Methods
                Database Searching
                Medicine and Health Sciences
                Health Care
                Health Education and Awareness
                Research and Analysis Methods
                Mathematical and Statistical Techniques
                Statistical Methods
                Meta-Analysis
                Physical Sciences
                Mathematics
                Statistics (Mathematics)
                Statistical Methods
                Meta-Analysis
                Medicine and Health Sciences
                Health Care
                Patients
                Outpatients
                Research and Analysis Methods
                Research Assessment
                Systematic Reviews
                Medicine and Health Sciences
                Health Care
                Health Care Providers
                Medical Doctors
                Physicians
                People and Places
                Population Groupings
                Professions
                Medical Doctors
                Physicians
                Custom metadata
                All relevant data are within the paper and its Supporting Information files, and can also be found within the primary manuscripts referenced.

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                Uncategorized

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