Deficits in facial emotional valence processing in older people with subjective memory complaints: Behavioral and electrophysiological evidence.

Abstract

Subjective memory complaints (SMCs), which occur in the absence of clinical memory deficits, may precede mild cognitive impairment (MCI) or Alzheimer's disease (AD). Some studies have reported a deficit in facial emotion processing in people with MCI or AD. However, it is unclear whether this deficit is also present in older people with SMCs. The present study used behavioral measurements and event-related potentials (ERPs) to investigate the facial emotion processing of 41 older people with SMCs and 38 without SMCs. The task contained 204 images displaying facial emotions (positive, negative, and neutral). In terms of behavior, our results showed that participants with SMCs were slower and less accurate than controls. In terms of ERPs, the N170 latency was longer in men with SMCs than in controls, whereas no differences were observed between groups in the P300 and late positive potential (LPP) latencies or amplitudes. Moreover, in participants with SMCs, higher P300 and LPP amplitudes were related to better performance on working memory, psychomotor speed, and attention. Additionally, women were faster and more accurate than men on the facial emotion-processing task. In sum, these results suggest that older people with SMCs may have deficits in the processing of facial expressions of emotion. However, this deficit seems to affect the structural encoding of faces, rather than the late stages of processing.