Journal ID (nlm-ta): Sci Adv
Journal ID (iso-abbrev): Sci Adv
Journal ID (publisher-id): SciAdv
Journal ID (hwp): advances
Title:
Science Advances
Publisher:
American Association for the Advancement of Science
ISSN
(Electronic):
2375-2548
Publication date Collection:
March
2020
Publication date
(Electronic):
11
March
2020
Volume: 6
Issue: 11
Electronic Location Identifier: eaax6328
Affiliations
[1
]Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary
and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK.
[2
]Imaging and data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca,
Cambridge CB4 0WG, UK.
[3
]Bioinformatics Group, Wageningen University, Wageningen 6708 PB, Netherlands.
[4
]Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB4 0WG, UK.
[5
]Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61
1BD, UK.
[6
]Centre for Discovery Brain Sciences, Simons Initiative for the Developing Brain, and
The Patrick Wild Centre, University of Edinburgh, Hugh Robson Building, George Square,
Edinburgh EH8 9XD, UK.
[7
]Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine
and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester
M13 9NT, UK.
[8
]National Physical Laboratory, Teddington, Middlesex TW11 0LW, UK.
[9
]Oncology Safety, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge
CB4 0WG, UK.
[10
]Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA,
UK.
[11
]Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK.
[12
]Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir
Alexander Fleming Building, South Kensington Campus, London SW7 2AZ, UK.
[13
]Department of Neurogenetics, Max Planck Institute for Experimental Medicine, Hermann-Rein-Strasse
3, D-37075 Goettingen, Germany.
[14
]Natural Products Metabolomics Group, Strathclyde Institute of Pharmacy and Biomedical
Sciences, University of Strathclyde, Glasgow G4 0RE, UK.
Author notes
Author information
Article
Publisher ID:
aax6328
DOI: 10.1126/sciadv.aax6328
PMC ID: 7065903
PubMed ID: 32195337
SO-VID: 7bb47b59-0b9f-4f9d-adc7-b14707b8f06b
Copyright © Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association
for the Advancement of Science. No claim to original U.S. Government Works. Distributed
under a Creative Commons Attribution License 4.0 (CC BY).
License:
This is an open-access article distributed under the terms of the
Creative Commons Attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original work is properly cited.
Funded by: doi http://dx.doi.org/10.13039/100004440, Wellcome Trust;
Award ID: Sir Henry Dale fellowship 104116/Z/14/Z
Funded by: doi http://dx.doi.org/10.13039/100004440, Wellcome Trust;
Award ID: 097820/Z/11/B
Funded by: doi http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: (BBSRC)-CASE studentship part funded by AstraZeneca
Funded by: doi http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/K008005/1
Funded by: doi http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/P003281/1
Funded by: doi http://dx.doi.org/10.13039/501100000289, Cancer Research UK;
Award ID: C596/A17196, Award 23982
Funded by: Multiple Sclerosis Society UK;
Award ID: Grant Reference 38