Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo.

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Abstract

Macrophages show extreme heterogeneity and different subsets have been characterized by their activation route and their function. For instance, macrophage subsets are distinct by acting differently under pathophysiological conditions such as inflammation and cancer. Macrophages also contribute to angiogenesis, but the role of various specific subsets in angiogenesis has not been thoroughly investigated.

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Journal

Journal ID (iso-abbrev): Angiogenesis

Title: Angiogenesis

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1573-7209

ISSN (Print): 0969-6970

Publication date (Electronic): Jan 2014

Volume: 17

Issue: 1

Affiliations

[1 ] Department of Molecular Genetics, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands.

Article

DOI: 10.1007/s10456-013-9381-6

PubMed ID: 24013945

SO-VID: 7b5bbd04-bc55-49e0-840a-97060a9bed40

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