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Serial Circulating Tumor DNA in Predicting and Monitoring the Effect of Neoadjuvant Chemoradiotherapy in Patients with Rectal Cancer: A Prospective Multicenter Study
Jiaolin Zhou ,
Changxi Wang ,
Guole Lin ,
Yi Xiao ,
Wenzhuo Jia ,
Gang Xiao ,
Qian Liu ,
Bin Wu ,
Aiwen Wu ,
Huizhong Qiu ,
Fuquan Zhang ,
Ke Hu ,
Huadan Xue ,
Zhanlong Shen ,
Zhenjun Wang ,
Jiagang Han ,
Beizhan Niu ,
Yaping Xu ,
Zicheng Yu ,
Ling Yang
January 04 2021
October 12 2020
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Abstract
We investigated the value of circulating tumor DNA (ctDNA) in predicting tumor response
to neoadjuvant chemoradiotherapy (nCRT), monitoring tumor burden, and prognosing survival
in patients with locally advanced rectal cancer (LARC).