Retained Descemet’s membrane following penetrating keratoplasty for Fuchs’ endothelial dystrophy: a case report of a post-operative complication

Abstract

Purpose

To report a case of retained Descemet’s membrane following penetrating keratoplasty in a patient suffering from Fuchs’ endothelial corneal dystrophy. The use of confocal microscopy, histopathological tissue analysis, and treatment options are discussed.

Methods

Case report of an 85-year-old man with a past ophthalmic history of atrophic macular degeneration, underwent a penetrating keratoplasty for Fuchs’ endothelial corneal dystrophy. Postoperative review revealed a retained retrocorneal membrane within the anterior chamber. Further surgery was performed to excise the membrane, with a subjective and objective postoperative improvement in visual acuity and without subsequent complications of the corneal graft.

Results

Histopathological assessment confirmed the clinical suspicion of a retained Descemet’s membrane, marrying with the initial histology from the corneal button excised during the penetrating keratoplasty, which showed only a very thin Descemet’s layer.

Conclusion

Retention of the Descemet’s membrane following penetrating keratoplasty is a rare but potential complication of this surgery, particularly in cases of Fuchs’ endothelial corneal dystrophy due to the thickened and abnormal histological nature of the endothelium and high index of suspicion is required.