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      A Biomolecular Toolbox for Precision Nanomotors

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          Analysis of nanoparticle delivery to tumours

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            Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC

            The cancer-cell-killing property of atezolizumab may be enhanced by the blockade of vascular endothelial growth factor-mediated immunosuppression with bevacizumab. This open-label, phase 3 study evaluated atezolizumab plus bevacizumab plus chemotherapy in patients with metastatic nonsquamous non-small-cell lung cancer (NSCLC) who had not previously received chemotherapy.
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              Neutrophil extracellular traps in immunity and disease

              Neutrophils are innate immune phagocytes that have a central role in immune defence. Our understanding of the role of neutrophils in pathogen clearance, immune regulation and disease pathology has advanced dramatically in recent years. Web-like chromatin structures known as neutrophil extracellular traps (NETs) have been at the forefront of this renewed interest in neutrophil biology. The identification of molecules that modulate the release of NETs has helped to refine our view of the role of NETs in immune protection, inflammatory and autoimmune diseases and cancer. Here, I discuss the key findings and concepts that have thus far shaped the field of NET biology.
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                Author and article information

                Contributors
                Journal
                Advanced Materials
                Advanced Materials
                Wiley
                0935-9648
                1521-4095
                February 23 2023
                : 2205746
                Affiliations
                [1 ]School of Chemical Engineering and Australian Centre for NanoMedicine The University of New South Wales Kensington New South Wales 2052 Australia
                [2 ]Graduate School of Biomedical Engineering The University of New South Wales Kensington New South Wales 2052 Australia
                [3 ]Ingham Institute for Applied Medical Research Liverpool New South Wales 2170 Australia
                [4 ]Department of Nanoengineering University of California San Diego La Jolla CA 92093 USA
                Article
                10.1002/adma.202205746
                79108f3f-c8da-4e4c-b1da-d58a23e55c70
                © 2023

                http://creativecommons.org/licenses/by-nc-nd/4.0/

                http://doi.wiley.com/10.1002/tdm_license_1.1

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