Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Antiepileptic drug (AED) exposure during pregnancy increases the risk of major congenital malformations (MCMs). The magnitude of this risk varies by AED exposure. Here we provide updated results from the UK Epilepsy and Pregnancy Register of the risk of MCMs after monotherapy exposure to valproate, carbamazepine and lamotrigine.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): J. Neurol. Neurosurg. Psychiatr.

Title: Journal of neurology, neurosurgery, and psychiatry

ISSN (Electronic): 1468-330X

ISSN (Print): 0022-3050

Publication date (Electronic): Sep 2014

Volume: 85

Issue: 9

Affiliations

[1 ] Neurology Department, Belfast Health and Social Care Trust, Royal Victoria Hospital, Belfast, Co Antrim, UK.

[2 ] Institute of Neurology, University College London.

[3 ] Department of Clinical Neurophysiology, Institute of Neurological Sciences, Southern General Hospital, Glasgow, UK.

[4 ] Academic Unit of Primary Medical Care, Samuel Fox House, University of Sheffield, Northern General Hospital, Sheffield, UK.

[5 ] Neurology Department, Luton & Dunstable Hospitals NHS Trust, Luton, UK.

[6 ] Department of Medical Genetics, Belfast Health and Social Care Trust, Belfast City Hospital, Belfast, Co Antrim, UK.

[7 ] RSCI, Beaumont Hospital, Dublin, Ireland.

[8 ] Department of Neurology, Beaumont Hospital, Dublin, UK.

Article

Publisher Item ID: jnnp-2013-306318

DOI: 10.1136/jnnp-2013-306318

PubMed ID: 24444855

SO-VID: 788929c5-9b5f-4812-bae2-f2cdb050cae6

History

Keywords: ANTICONVULSANTS,EPILEPSY

Data availability:

Keywords: ANTICONVULSANTS, EPILEPSY

Comments

Comment on this article

scite_

Cited by 69

See all cited by