Minimal physiologically-based pharmacokinetic model to investigate the effect of pH dependent FcRn affinity and the endothelial endocytosis on the pharmacokinetics of anti-VEGF humanized IgG1 antibody in cynomolgus monkey

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Journal

Title: European Journal of Pharmaceutical Sciences

Abbreviated Title: European Journal of Pharmaceutical Sciences

Publisher: Elsevier BV

ISSN (Print): 09280987

Publication date Created: December 2018

Publication date (Print): December 2018

Volume: 125

Pages: 130-141

Article

DOI: 10.1016/j.ejps.2018.09.015

PubMed ID: 30248389

SO-VID: 778c6c1d-279e-4bb2-b7da-89089cd165ad

License:

https://www.elsevier.com/tdm/userlicense/1.0/

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