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      Incidence of periprosthetic joint infection after primary total hip arthroplasty is underestimated: a synthesis of meta-analysis and bibliometric analysis

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          Abstract

          The American Musculoskeletal Society updated the diagnostic criteria for periprosthetic joint infection (PJI) in 2011 and 2018. However, the overall incidence of PJI since the introduction of these new standards has not been assessed. In order to fill this knowledge gap, a single-group meta-analysis was conducted using articles obtained from several databases, focusing on the incidence of PJI after primary total hip arthroplasty (THA). Our study revealed a significant difference in the incidence of PJI reported by different national or regional databases. Moreover, most cases of PJI were found to be underestimated. This highlights the crucial need for standardized diagnostic criteria and monitoring methods to accurately identify and track cases of PJI. Furthermore, a bibliometric analysis was conducted to provide a comprehensive overview of the current state of research on PJI after THA. This analysis explored the most productive countries, organizations, journals, and individuals in this research area. Additionally, it identified the research trends and hotspots of the last decade, highlighting the advancements and areas of focus in this field. By conducting these analyses, the study aims to contribute to the understanding of PJI after THA and provide valuable insights for clinicians, researchers, and policymakers involved in the management of this condition.

          Supplementary Information

          The online version contains supplementary material available at 10.1186/s13018-023-04060-5.

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          Most cited references54

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          Assessing heterogeneity in meta-analysis: Q statistic or I2 index?

          In meta-analysis, the usual way of assessing whether a set of single studies is homogeneous is by means of the Q test. However, the Q test only informs meta-analysts about the presence versus the absence of heterogeneity, but it does not report on the extent of such heterogeneity. Recently, the I(2) index has been proposed to quantify the degree of heterogeneity in a meta-analysis. In this article, the performances of the Q test and the confidence interval around the I(2) index are compared by means of a Monte Carlo simulation. The results show the utility of the I(2) index as a complement to the Q test, although it has the same problems of power with a small number of studies.
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            The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria

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              Prosthetic joint infection.

              Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the global health care industry. While a small minority of joint arthroplasties will become infected, appropriate recognition and management are critical to preserve or restore adequate function and prevent excess morbidity. In this review, we describe the reported risk factors for and clinical manifestations of PJI. We discuss the pathogenesis of PJI and the numerous microorganisms that can cause this devastating infection. The recently proposed consensus definitions of PJI and approaches to accurate diagnosis are reviewed in detail. An overview of the treatment and prevention of this challenging condition is provided.
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                Author and article information

                Contributors
                hw13802516062@163.com
                weiqshi@126.com
                290021339@qq.com
                Journal
                J Orthop Surg Res
                J Orthop Surg Res
                Journal of Orthopaedic Surgery and Research
                BioMed Central (London )
                1749-799X
                21 August 2023
                21 August 2023
                2023
                : 18
                : 610
                Affiliations
                [1 ]GRID grid.411866.c, ISNI 0000 0000 8848 7685, The Third School of Clinical Medicine, , Guangzhou University of Chinese Medicine, ; Guangzhou, China
                [2 ]Guangdong Research Institute for Orthopedics and Traumatology of Chinese Medicine, Guangzhou, China
                [3 ]GRID grid.411866.c, ISNI 0000 0000 8848 7685, The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, ; Guangzhou, China
                Article
                4060
                10.1186/s13018-023-04060-5
                10440885
                37605235
                766613ea-fb31-4e85-b235-04cc8ad5c524
                © BioMed Central Ltd., part of Springer Nature 2023

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 21 May 2023
                : 30 July 2023
                Funding
                Funded by: General Projects of National Natural Science Foundation of China
                Award ID: 81873327
                Award ID: 82274544
                Award Recipient :
                Funded by: National Natural Science Foundation of China Youth Science Foundation
                Award ID: 82004392
                Award Recipient :
                Categories
                Research
                Custom metadata
                © BioMed Central Ltd., part of Springer Nature 2023

                Surgery
                periprosthetic joint infection,pji,arthroplasty,tha,incidence,epidemiology,bibliometrics,meta-analysis
                Surgery
                periprosthetic joint infection, pji, arthroplasty, tha, incidence, epidemiology, bibliometrics, meta-analysis

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