Current investigation emphasizes the evaluation of entropy in a porous medium of Williamson nanofluid (WNF) flow past an exponentially extending horizontal plate featuring Parabolic Trough Solar Collector (PTSC). Two kinds of nanofluids such as copper-methanol (Cu-MeOH) and alumina-methanol (Al 2O 3-MeOH) were tested, discussed and plotted graphically. The fabricated nanoparticles are studied using different techniques, including TDDFT/DMOl 3 method as simulated and SEM measurements as an experimental method. The centroid lengths of the dimer are 3.02 Å, 3.27 Å, and 2.49 Å for (Cu-MeOH), (Al 2O 3-MeOH), and (Cu-MeOH-αAl-MOH), respectively. Adequate similarity transformations were applied to convert the partial differential equation (PDEs) into nonlinear ordinary differential equations (ODEs) with the corresponding boundary constraints. An enhancement in Brinkmann and Reynolds numbers increases the overall system entropy. WNF parameter enhances the heat rate in PTSC. The thermal efficiency gets elevated for Cu-MeOH than that of Al 2O 3-MeOH among 0.8% at least and 6.6% in maximum for varying parametric values.