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      Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial

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          Abstract

          <p class="first" id="d5084202e219">Treatment-resistant major depressive disorder is common; repetitive transcranial magnetic stimulation (rTMS) by use of high-frequency (10 Hz) left-side dorsolateral prefrontal cortex stimulation is an evidence-based treatment for this disorder. Intermittent theta burst stimulation (iTBS) is a newer form of rTMS that can be delivered in 3 min, versus 37·5 min for a standard 10 Hz treatment session. We aimed to establish the clinical effectiveness, safety, and tolerability of iTBS compared with standard 10 Hz rTMS in adults with treatment-resistant depression. </p>

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          Author and article information

          Journal
          The Lancet
          The Lancet
          Elsevier BV
          01406736
          April 2018
          April 2018
          : 391
          : 10131
          : 1683-1692
          Article
          10.1016/S0140-6736(18)30295-2
          29726344
          741850b8-1a41-4d45-b1a3-9714b0b47582
          © 2018

          http://www.elsevier.com/tdm/userlicense/1.0/

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